The wave load of jack-up platform is calculated based on SESAM software. In view of the wave load calculation in the pile standing state, it is necessary to select the environmental parameters, wave theory, and hydrodynamic coefficient; in view of the wave load calculation in the navigation state, it is necessary to establish the wet surface model and mass model, set the parameters, and forecast the wave load. The calculation method is of certain guiding significance for the design of other similar structures.