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新型人工机械心脏瓣膜加速疲劳试验

武亮亮,  周丰,  孙鸿,  王进,  刘丽,  黄楠

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文章导航 > 西南交通大学学报  > 2014 >  27(3): 530-535.
武亮亮, 周丰, 孙鸿, 王进, 刘丽, 黄楠. 新型人工机械心脏瓣膜加速疲劳试验[J]. 西南交通大学学报, 2014, 27(3): 530-535. doi: 10.3969/j.issn.0258-2724.2014.03.025
引用本文: 武亮亮, 周丰, 孙鸿, 王进, 刘丽, 黄楠. 新型人工机械心脏瓣膜加速疲劳试验[J]. 西南交通大学学报, 2014, 27(3): 530-535. doi: 10.3969/j.issn.0258-2724.2014.03.025
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WU Liangliang, ZHOU Feng, SUN Hong, WANG Jin, LIU Li, HUANG Nan. Accelerated Fatigue Test in Vitro of the New Mechanical Heart Valve[J]. Journal of Southwest Jiaotong University, 2014, 27(3): 530-535. doi: 10.3969/j.issn.0258-2724.2014.03.025
Citation: WU Liangliang, ZHOU Feng, SUN Hong, WANG Jin, LIU Li, HUANG Nan. Accelerated Fatigue Test in Vitro of the New Mechanical Heart Valve[J]. Journal of Southwest Jiaotong University, 2014, 27(3): 530-535. doi: 10.3969/j.issn.0258-2724.2014.03.025
shu

新型人工机械心脏瓣膜加速疲劳试验

doi: 10.3969/j.issn.0258-2724.2014.03.025
基金项目: 

国家自然科学基金资助项目（20973134）

国家高技术研究发展计划资助项目（2006AA02A139）

详细信息
    通讯作者:

    黄楠（1956-），男，教授，博士生导师，研究方向材料学及表面改性，E-mail：nhuang@263.net

Accelerated Fatigue Test in Vitro of the New Mechanical Heart Valve

    摘要
  • 摘要: 为评价新型瓣膜的开闭状态及疲劳特性，采用TH—2200型人工心瓣疲劳寿命测试仪对聚甲醛瓣叶的双叶心脏瓣膜和ON-X心脏瓣膜进行疲劳实验，并利用高速摄像机对瓣膜的开启与关闭情况进行跟踪，考察瓣膜的瞬时运动状态.实验结果发现，在体外加速疲劳实验中，新型双叶心脏瓣膜与ON-X心脏瓣膜在相同频率下具有相近的开启关闭周期，在瓣叶开启至极限位置时都有抖动产生，该瓣膜经3×108次疲劳测试后，瓣环无明显磨损，瓣叶转动灵活，心瓣正常工作.

     

    Abstract: In order to evaluate the opening and closing states and fatigue properties of a new type of polyoxymethylene heart valve, accelerated fatigue tests were performed on the polyoxymethylene heart valve and an ON-X heart valve using the heart valve prostheses fatigue tester (TH-2200). The opening and the closing positions of the leaflets were tracked using the high speed camera, and the instantaneous motion states of valves were investigated. The results show that the new heart valve had a similar opening-closing cycle at the same frequency with the ON-X heart valve in in vitro accelerated fatigue experiments, and the leaflets of both the valves would generate jitters when they opened to the limit position. After 3×108 cycles of fatigue tests, no obvious wear was found on the valve ring, the valve leaflets rotated flexibly, and the heart valve was working properly.

     

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    • 参考文献(15)
  • RAHIMTOOLA S H. The year in valvular heart disease[J]. Journal of the American College of Cardiology, 2012, 60(2): 85-95.
    MOHAMMADI H, MEQUANINT K. Prosthetic aortic heart valves: Modeling and design[J]. Medical Engineering and Physics, 2011, 33(2): 131-147.
    DASI L P, MURPHY D W, GLEZER A, et al. Passive flow control of bileaflet mechanical heart valve leakage flow[J]. Journal of Biomechanics, 2008, 41(6): 1166-1173.
    ZILLA P, BRINK J, HUMAN P, et al. Prosthetic heart valves: catering for the few[J]. Biomaterials, 2008, 29(4): 385-406.
    HAGGAG M Y A. In-vitro engineering testing of prosthetic cardiac valves[J]. Journal of Clinical Engineering, 1989, 14(6): 469-477.
    NUGENT A H, SCOTTEN L N, WALKER D K, et al. Accelerated fatigue tests of heart valves: a preliminary data base[C]//Proceedings of the 37th Annual Conference on Engineering in Medicine and Biology. Los Angeles: Alliance for Engineering in Medicine and Biology, 1984: 149-150.
    JOZWIK K, KARCZEMSKA A. The new generation Ti6Al4V artificial heart valve with nanocrystalline diamond coating on the ring and with derlin disc after long-term mechanical fatigue examination[J]. Diamond and Related Materials, 2007, 16(4-7): 1004-1009.
    YUN B M, WU J, SIMON H A, et al. A numerical investigation of blood damage in the hinge area of aortic bileaflet mechanical heart valves during the leakage phase[J]. Annals of Biomedical Engineering, 2012, 40(7): 1468-1485.
    XENOS M, GIRDHAR G, ALEMU Y, et al. Device thrombogenicity emulator (DTE): design optimization methodology for cardiovascular devices: a study in two bileaflet MHV designs[J]. Journal of Biomechanics, 2010, 43(12): 2400-2409.
    席葆树, HWANG N H C, 吴嘉. 人工心脏瓣膜体外加速疲劳试验[C]//第七届全国生物力学学术会议. 西安:[s.n.], 2003: 7-8.
    康振黄, 陈君楷, 袁支润, 等. 一种新型人工机械心瓣:双叶翼型瓣的开发研究[J]. 中国生物医学工程学报, 1993, 12(3): 168-177. KANG Zhenhuang, CHEN Junkai, YUAN Zhirun, et al. Development of a new mechanical artificial heart valve-bileaflet with cambered profile[J]. Chinese Journal of Biomedical Engineering, 1993, 12(3): 168-177.
    邹盛铨, 闫书川, 樊瑜波, 等. 双叶翼型机械瓣的体外加速疲劳试验研究[J]. 四川大学学报:工程科学版, 2001, 33(5): 107-111. ZOU Shengquan, YAN Shuchuan, FAN Yubo, et al. Study on the acclerated fatigue test of bileaflet wing profile mechanical valve[J]. Journal of Sichuan University: Engineering Science Edition, 2001, 33(5): 107-111.
    李海波, 王武军, 梁勇, 等. 膨体聚四氟乙烯人工心脏瓣膜体外加速疲劳的实验研究[J]. 南方医科大学学报, 2006, 26(12): 1749-1752. LI Haibo, WANG Wujun, LIANG Yong, et al. Accelerated fatigue test in vitro of expanded polytetrafluoroethylene artificial heart valve[J]. Journal of Southern Medical University, 2006, 26(12): 1749-1752.
    褚银平, 程金莲, 刘爱军, 等. 脉动流下机械心脏瓣膜瓣阀开启状态的评价[J].中国组织工程研究, 2012, 16(40): 7480-7485. CHU Yinping, CHENG Jinlian, LIU Aijun, et al. Evaluation on opening status of the mechanical heart valve in vitro under pulsatile flow[J]. Chinese Journal of Tissue Engineering Research, 2012, 16(40): 7480-7485.
    FENG Z, NAKAMURA T, FUJIMOTO T, et al. In vitro investigation of opening behavior and hydrodynamics of bileaflet valves in the mitral position[J]. Artificial Organs, 2002, 26(1): 32-39.
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出版历程
  • 收稿日期:  2013-04-16
  • 刊出日期:  2014-06-25

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