LOSS OF NUCLEUS BASALIS MAGNOCELLULARIS，BUT NOT SEPTAL，CHOLINERGIC NEURONS CORRELATES WITH PASSIVE AVOIDANCE IMPAIRMENT IN RA

ＬＯＳＳＯＦＮＵＣＬＥＵＳＢＡＳＡＬＩＳＭＡＧＮＯＣＥＬＬＵＬＡＲＩＳ，ＢＵＴＮＯＴＳＥＰＴＡＬ，ＣＨＯＬＩＮＥＲＧＩＣＮＥＵＲＯＮＳ　ＣＯＲＲＥＬＡＴＥＳＷＩＴＨＰＡＳＳＩＶＥＡＶＯＩＤＡＮＣＥＩＭＰＡＩＲＭＥＮＴＩＮＲＡＴＳＴＲＥＡＴＥＤ　ＷＩＴ...     

NEW SET OF OPERATOR-VALUED BESSEL FUNCTIONS,THE HOLOMORPHIC DISCRETE SERIES AND ITS ANALYTIC CONTINUATION

ＮＥＷＳＥＴＯＦＯＰＥＲＡＴＯＲ┐ＶＡＬＵＥＤＢＥＳＳＥＬＦＵＮＣＴＩＯＮＳ，ＴＨＥＨＯＬＯＭＯＲＰＨＩＣＤＩＳＣＲＥＴＥＳＥＲＩＥＳＡＮＤＩＴＳＡＮＡＬＹＴＩＣＣＯＮＴＩＮＵＡＴＩＯＮ＊ＤｉｎｇＨｏｎｇｍｉｎｇ（丁鸿明）（Ｓｔ．ＬｏｕｉｓＵｎｉｖｅ...     

DYNAMIC CHANGES IN Giα2 LEVELS IN THE RAT HEART ASSOCIATED WITH IMPAIRED CARDIAC FUNCTION FOLLOWING ACUTE MYOCARDIAL INFA RCT

ＤＹＮＡＭＩＣＣＨＡＮＧＥＳＩＮＧｉα２ＬＥＶＥＬＳＩＮＴＨＥＲＡＴＨＥＡＲＴＡＳＳＯＣＩＡＴＥＤＷＩＴＨＩＭＰＡＩＲＥＤＣＡＲＤＩＡＣＦＵＮＣＴＩＯＮＦＯＬＬＯＷＩＮＧＡＣＵＴＥＭＹＯＣＡＲＤＩＡＬＩＮＦＡＲＣＴＩＯＮＳｋｉＢｉｎｇ；Ｊ．Ｅ．Ｈｅａ...     

A VNTR ELEMENT ASSOCIATED WITH STEROID SULFATAES GENE DELETIONS STIMULATES RECOMBINATIONIN CULTURED CELLS

ＡＶＮＴＲＥＬＥＭＥＮＴＡＳＳＯＣＩＡＴＥＤＷＩＴＨＳＴＥＲＯＩＤＳＵＬＦＡＴＡＥＳＧＥＮＥＤＥＬＥＴＩＯＮＳＳＴＩＭＵＬＡＴＥＳ　ＲＥＣＯＭＢＩＮＡＴＩＯＮＩＮ　ＣＵＬＴＵＲＥＤ　ＣＥＬＬＳＧｏｎｇＹａｎ；Ｘ．Ｍ．Ｌｉ，Ｌ．Ｊ．Ｓｈａｐｉｒｏ（Ｄｅ...     

CHANGES OF SUPEROXIDE FREE RADICAL （O2） IN CHILDREN WITH ACUTE GLOMERULONEPHRITIS AND ITS CHANGES AFTER THE RECOVERY

ＣＨＡＮＧＥＳＯＦＳＵＰＥＲＯＸＩＤＥＦＲＥＥＲＡＤＩＣＡＬ（Ｏ２）ＩＮＣＨＩＬＤＲＥＮＷＩＴＨＡＣＵＴＥＧＬＯＭＥＲＵＬＯＮＥＰＨＲＩＴＩＳＡＮＤＩＴＳＣＨＡＮＧＥＳＡＦＴＥＲＴＨＥＲＥＣＯＶＥＲＹＫｏｎｇＸｉａｎｇｚｈｅｎ；ＢｉＨｏｎｇ；ＺｈｕＸ...     

VARIABLE CUTOFFF REQUENCY NONLINEAR DIGITAL FILTER: II-TWO-DIMENSION

ＶＡＲＩＡＢＬＥＣＵＴＯＦＦＦＲＥＱＵＥＮＣＹＮＯＮＬＩＮＥＡＲＤＩＧＩＴＡＬＦＩＬＴＥＲ：ＩＩ－ＴＷＯ┐ＤＩＭＥＮＳＩＯＮ＊ＧｏＨｏｎｇ（古红）ＺｈｕＹｉｓｈｅｎｇ（朱贻盛）（ＩｎｓｔｉｔｕｔｅｏｆＢｉｏｍｅｄｉｃａｌＥｎｇｉｅｅｒｉｎｇ，Ｓｈａｎ...     

THE STUDY OF RED BLOOD CELL IMMUNE FUNCTIONS AND THEIR RELATIONSHIP WITH T LYMPHOCYTE SUBSETS AND FREE RADICAL IN CHILDREN WI

ＴＨＥＳＴＵＤＹＯＦＲＥＤＢＬＯＯＤＣＥＬＬＩＭＭＵＮＥＦＵＮＣＴＩＯＮＳＡＮＤＴＨＥＩＲＲＥＬＡＴＩＯＮＳＨＩＰＷＩＴＨＴＬＹＭＰＨＯＣＹＴＥＳＵＢＳＥＴＳＡＮＤＦＲＥＥＲＡＤＩＣＡＬＩＮＣＨＩＬＤＲＥＮＷＩＴＨＭＹＯＣＡＲＤＩＴＩＳ（ＡＢＳＴＲＡ...     

VARIABLE CUTOFF FREQUENCY NONLINEAR DIGITAL FILTERS: I-ONE-DIMENSION

ＶＡＲＩＡＢＬＥＣＵＴＯＦＦＦＲＥＱＵＥＮＣＹＮＯＮＬＩＮＥＡＲＤＩＧＩＴＡＬＦＩＬＴＥＲＳ：Ｉ－ＯＮＥ┐ＤＩＭＥＮＳＩＯＮ＊ＧｕＨｏｎｇ（古红）ＺｈｕＹｉｓｈｅｎｇ（朱贻盛）（ＩｎｓｔｉｔｕｔｅｏｆＢｉｏｍｅｄｉｃａｌＥｎｇｉｎｅｅｒｉｎｇ，Ｓｈａ...     

THE DETECTION OF P53 GENE IN HUMAN CERVICAL CARCINOMA WITH AND WITHOUT HUMAN PAPILLOMAVIRUS INFECTION

ＴＨＥＤＥＴＥＣＴＩＯＮＯＦＰ５３ＧＥＮＥＩＮＨＵＭＡＮＣＥＲＶＩＣＡＬＣＡＲＣＩＮＯＭＡＷＩＴＨＡＮＤＷＩＴＨＯＵＴＨＵＭＡＮＰＡＰＩＬＬＯＭＡＶＩＲＵＳＩＮＦＥＣＴＩＯＮＳｕｎＹｉ（孙毅）；ＳｉＬｕｓｈｅｎｇ（司履生）ＳｕｎＹｉ；ＳｉＬｕｓｈｅｎ...     

A STUDY OF SEROTONERGIC NEURONS ON PATHWAY FROM THE MEDULLARYRAPHE NUCLEI TO THE CEREBELLAR CORTEX IN THE KITTEN BY USING FLU

ＡＳＴＵＤＹＯＦＳＥＲＯＴＯＮＥＲＧＩＣＮＥＵＲＯＮＳＯＮＰＡＴＨＷＡＹＦＲＯＭＴＨＥＭＥＤＵＬＬＡＲＹＲＡＰＨＥＮＵＣＬＥＩＴＯＴＨＥＣＥＲＥＢＥＬＬＡＲＣＯＲＴＥＸＩＮＴＨＥＫＩＴＴＥＮＢＹＵＳＩＮＧＦＬＵＯＲＥＳＣＥＮＴＭＩＣＲＯＳＰＨＥＲＥＳ...     

人体真菌还原硝酸盐作用的研究及其意义

为了研究人体所带真菌是否具有还原硝酸盐为亚硝酸盐的作用,从而研讨人类肿瘤病因中真菌因素的可能作用机理,我们用由妇女阴道及宫颈部分离出的多种真菌,进行了还原硝酸盐实验研究,并对其结果在医学上的意义作了讨论。实验结果表明短密青霉还原硝酸盐阳性率很高,略阳为72.73%(56/77),五峰为67.65%(23/34)。酵母及假丝酵母属真菌实验菌株数很少,还原阳性率也低。有些实验真菌如白曲霉、土曲霉、黄柄曲霉、屡地青霉、产紫青霉以及砖红酵母虽然还原阳性率很高,但由于这些真菌在综考中检出率很低,实验菌株数也少,故在肿瘤病因上的意义可能不大。     

Nine pathogenic fungi of waterhyacinth isolated in China

The native pathogens of waterhyacinth in China, were studied and compared on pathogenicity by Koch＇s postulate. Nine pathogenic fungi, YBH, YBB, YB, YYX, YY, YBA1, YBA2, YBA3 and YYB12, were isolated from diseased waterhyacinth plants, and collected from Zhejiang province and Shanghai. According to cultural characteristics, the nine isolates were preliminarily identified. Isolates YBH and YBB were Collectotrichum sp.; YB, YYX and YY were placed in fungi imperfecti; the isolates YBA1, YBA2, YBA3 and YYB12 were Alternaria sp. The isolate YBH was the highly virulent with a disease index （DI） of 65.28% after one month inoculation. The isolate YBA3 was equily virulent, with the disease index of 6770 after 7 day introduction. These two pathogens appear to have the potential as biocontrol agents and they deserve further study.     

Some Key Technologies of a New-type CNC Curve Grinding Machine

This paper presented a new-type CNC curve grinding machine, in order to conquer the disadvantages of conventional NC curve grinding machine and improve surface quality, dimensional accuracy and machining efficiency. The new-type grinder adopts some high and new technologies: ① the normal tracing device could make grinding wheel coincide with the normal direction of the machining points in work piece, and improve surface quality and dimensional accuracy; ② the digital image on-line recognition system could monitor machining process and compensate wheel wear in real time; ③ linear motor drive mechanism could realize the exact adjustment of the grinding head digitally and increase the machining efficiency. The math models of normal tracing and circular tolerance zone were presented. The experimental results show that the new-type CNC curve grinding machine equipped with the three devices mentioned above is easy to realize the precision grinding of any complex curve, and improve surface quality, dimensional accuracy and machining efficiency.     

ANALYSIS OF FUNGI IN MUSHROOM COMPOST USING PCR AND TGGE OF RIBOSOMAL DNA

Introduction　　 Preparation of a uniform and productive sub-strate forthe growth of Agaricusbisporusis impor-tant in commercial edible mushroom production.The traditional production of synthetic compostforthe growth of Agaricus bisporus consists of an un-controlled outdoor composting process called phase ,followed by an indoor,temperature- controlledprocess called phase . Phase involves a pas-teurisation followed by substrate conditioning,which promotes the selectivity of the compost fo…     

角膜实质层胶原纤维三维交叉网状结构的进一步探讨兼论弹性纤维 Ⅰ.兔角膜的LM、TEM及SLM观察

本文应用常规及自行设计的标本制备法对8个正常兔角膜实质层纤维成分分别做了LM、TEM及SEM观察。结果表明:①胶原纤维排列成三维交叉网状結构,后者在约500μm范围内呈板状,称微板,微板相互吻合成微板网;②在LM下所见的厚约4—9μm的“胶原纤維”或“板层”,实际是微板网的垂直切面,⑧文献中的板层结构TEM照片实为其网状结构的一部分,④在胶原纤维之间有少量分支交错的细小纤维,可能是弹性纤维。     

小半径曲线钢轨非对称打磨廓形设计方法

为设计可提升列车小半径曲线通过性能的钢轨非对称打磨目标廓形，对中国现有CN60钢轨廓形进行了几何推导；以钢轨廓形几何参数作为设计变量，以车辆系统多体动力学指标作为综合目标函数，考虑钢轨打磨约束条件，提出了一种针对小半径曲线钢轨非对称打磨廓形的多目标数值优化模型；基于差分进化算法编写了相应的数值计算程序，并选择合理的计算参数求解了优化模型；根据实际线路参数分析了优化后钢轨打磨廓形的轮轨接触几何特性，并验证了列车的小半径曲线动力学性能。研究结果表明:提出的优化方法具有较快的计算速度，优化模型仅迭代了97次即可获得理想的钢轨打磨廓形；非对称打磨使内外钢轨具有差异性的打磨位置与打磨深度，将轮轨对中位置向轨道内侧移动了约10 mm，且不会改变轮缘处的轮轨匹配特性，有效增大了轮对横移10 mm范围内的轮对滚动圆半径差与轮轨接触角差，降低了列车在通过小半径曲线时的轮对横移、轮轨横向力、脱轨系数和轮重减载率，提高了转向架的横向稳定性和轮轨磨耗性能；虽然该打磨方式获得的钢轨廓形增大了轮轨接触应力，但并不会引起轮轨塑性变形。由此可见，该设计方法为提高列车的中小半径曲线通过能力提供了一种可行途径。      

土贝母皂甙对家兔单纯疱疹病毒性角膜炎的作用

目的评价土贝母皂甙(tubei moside,Tu)治疗家兔单纯疱疹病毒性角膜炎(herpes si mplex keratitis,HSK)的效果。方法在地鼠肾细胞BHK-21上进行单纯疱疹病毒I型(HSV-1型)SM44毒株复苏,制作兔HSK模型。家兔分为0.2g/L Tu、无环鸟苷(ACV)和生理盐水(NS)3组,采用裂隙灯显微镜、扫描电镜和透射电镜观察眼部病变的变化。结果0.2g/L Tu、无环鸟苷和生理盐水组第6~8天角膜病变分值分别为3.13~3.5、1.75~1.88和3.83~3.88,第14天时为2.07、1.13和2.77,3组间比较,均有显著性差异(P<0.01)。0.2g/L Tu可以显著缩小角膜病变面积,促进角膜上皮细胞的修复,其作用优于生理盐水组,但不及ACV组。结论Tu点眼剂治疗实验性HSK有一定的疗效,但尚不及ACV。     

过度磨耗钢轨的打磨廓形设计方法

针对过度磨耗钢轨的打磨，提出一种以圆弧切点为关键参数的钢轨廓形设计方法；以轮轨接触位置为优化区域，以钢轨磨耗和打磨材料去除量作为优化目标函数，以廓形边界范围、凹凸性、脱轨系数和轮轨横向力为约束条件，建立磨耗钢轨打磨设计廓形多目标函数；集成多元模拟退火寻优算法进行求解；为了得到能代表重载线路曲线区段的钢轨廓形，作为优化的输入数据，采用最小二乘距离算法、算术平均算法、加权平均算法和散点重构算法得出4种钢轨代表廓形；使用Pearson相关系数、Kendall秩相关系数和Spearman秩相关系数计算出4种算法的钢轨代表廓形与实测廓形接触点概率分布曲线的相关性，取相关性最高的代表廓形为等效重载线路曲线区段的实际廓形；对某重载线路过度磨耗钢轨的经济性打磨廓形以及采用圆弧型廓形设计方法的优化廓形进行分析。分析结果表明:优化廓形与现场打磨廓形相较，截面廓形磨削量减少69.56 mm2，下降64.98%，脱轨系数小幅增大，轮轨横向力基本不变，轮对横移变化较小，曲线通过性能相近，80万次通过量下的磨耗面积增加2.19 mm2，钢轨的磨耗速率略微增大，整体仍延长了钢轨寿命。      

超声振动辅助端面磨削表面温度场研究

对Nd-Fe-B烧结永磁材料恒压力径向振动辅助端面磨削的温度场进行研究.分析了恒压力振动磨削过程中磨削力和磨削速度的特点;完成了磨削表面温度场的理论计算和实验验证,发现恒压力振动辅助端面磨削时温度比相同条件下无超声振动时有所上升,并指出了发生这种现象的几个主要原因.通过对磨削温度场的研究可以在获得满意加工效果的同时,控制磨削烧伤的发生,进而充分发挥复合加工技术的优点.     

海洋真菌AP2T1菌株介质阻挡放电等离子体诱变初步研究

对药源海洋真菌介质阻挡放电等离子体诱变的实验方法初步研究.对等离子体放电诱变条件进行了探索,比较了等离子体单独诱变与等离子体-不同化学诱变剂复合诱变的诱变效果,并对两个较合适的诱变方式进行了致死曲线的研究,且对海洋真菌AP2T1菌株进行了初步规模的诱变处理与活性筛选实验.研究发现等离子体单独诱变及等离子体-氯化锂复合诱变较适合该菌株,且该海洋真菌孢子对等离子体的致死曲线与前人报道的细菌相似,并发现等离子体对老化失活的出发菌株可能具有激活作用.研究结果表明,介质阻挡放电等离子体可能是一种较适合海洋药源真菌诱变育种的新手段,值得继续完善、深入研究.