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1.
本文是文[2]的继续,先给出集值u0-增算子的概念,然后在序条件下讨论了u0-凹(凸)算子不动点的若干性质,得出[1,3]中在集值情形下的相应结果.  相似文献   

2.
Cytomegalovirus (CMV )infectionisoneofthemostcommonposttransplantcomplicationsandwasassociatedwithanincreasedmorbidityandmor talityintransplantrecipients[1,2 ] .Duringthefirst 4monthsafterrenaltransplantation ,theincidenceofactiveCMVinfectionisapproximately 5 0 % -90 % [3] .Recently ,manyresearchershavefoundthatCMVcouldaffecttheimmunityofhumanbe ing .CMVinfectionisalsoariskfactorforacuteandchronicrejectionofrenalallograftanddirectlycorrelateswithdecreased patientandallograftsur vival[4 - 7…  相似文献   

3.
IntroductionltiswellknownthatmetallmpicalstrUcforeofsteelsandheattransferarefullycouPled.PhasechangesdependontemPertheeevoluton,whereastemPertheeisinfluencedbycontrastsofmaterialcharacteristicsbetWeenphasesandlatenheateffects.AlotofworkhasbeenpefformedonthssubeCt,andclassicalmodelsarenowwidelyimPlementedintofiniteelementcomPutercodes[l][2][31[4][5][61.Thesemodelsaregenerallybasedonf.AVramityPekinetics[7][8]l9]Whnthephasechangeisgovernedbydiffusion,.TheKoistinen-Marburgerlaw[l0]fOrmfornsi…  相似文献   

4.
Small celllungcancer (SCLC )isasubtyperepresentingapproximately 15 %to 2 0 %ofallpri marylungcarcinomaoccurringinChina .Ingener al,SCLCishighlysensitivetochemotherapyandhasafrequenttendencytometastasizeatanearlystage .Thus ,itisveryimportanttomakeanearlydiagnosisforthetreatmentofSCLC patients .NSEhaslongtermbeenusedasSCLCearlydiagnosismarkerinclinic[1] .However ,therelativelyhighfalse positiveratehasforcedthedoctorstolookforthemorespecificandsensitivemarker[2 ] .SincePro gastrin relea…  相似文献   

5.
Acuteliverfailure(ALF)isaseveresymptomcausedbykindsofreasons ,suchaschemicalandvirologicalones.Becauseofthelife threatingcom plicationsofacuteliverfailure ,75 %of patientswilldiewithinafewdaysofonset.TherewasnosatisfactorytreatmentforALFexceptlivertrans plantation .Althoughlivertransplantationissuccess ful,withasurvivalraterangingfrom 6 0 %to80 % [1] .Thereisashortageofavailabledonoror gans.Onlyalittleamountofpatientsreceivedlivertransplantation[2 ] .Sothereisagreatneedforanef fectiveliver…  相似文献   

6.
运用随机不动点理论,得到了四阶随机微分方程边值问题(y(4)(ω,t)=f(ω,t,y(ω,t),y"(ω,t)),ω∈Ω,0相似文献   

7.
Thioredoxin (TRX)isanoxidoreductaseen zyme,withamolecularweightof 1 2kD .Itwasi dentifiedoriginallyinE .coliasanhydrogendonorforribonucleotidereductaseanddeoxyribonucle otidesynthesis[1] .Thegeneofhumanthioredoxin(hTRX)islocatedonchromosome 3 p1 1 p1 2 ,withafulllengthof 1 3Kb .Theopenreadingframe ( 3 1 5nucleotideslong)codedforaproteinof 1 0 4aminoacids[2 ,3] .ManyfunctionsofTRXhavebeenre ported,whichincludethefollowing :TheTRXsystem (whichincludesHADPHasaprotondonor,TRXreductase ,…  相似文献   

8.
IntroductionTherearemanyfacorswhichinfluencethedistortonofworkpieceandeveryheattreatInentengineerssWandtrytofindordevelopmodelsandsimulationmethodstoestimateandreducedistortonorwarpage.VariousmodelshavebeenandbeinginvestigatOdtoestimatetheinduenceoffacorsontfansformahonkinetics,hardness,residualstressanddistOrtionarerCPortCdatmanyconferences,.HowevefHEARTS[l]andafewofothermodelshavebeendeveloPedandcontrthutingtounderstandandPredicttheialluenceofrelatngfacors[2-1o].EVenstillmanyhazardous…  相似文献   

9.
Hirschsprung’sdisease (HD)isacongenitalmalformationwithanincidenceofonein 50 0 0livenewborns .Theabsenceofintramuralintestinalgan gliaofMeissnerandAuerbachresultsinpoorcoor dinationofpropulsivemovementandhencefunc tionalintestinalobstruction .Patientsaretreatedsur gicallywithremovaloftheaffectedintestine[1 ] .In1994 ,twomajorgenesassociatedwithHDwererecognized .First ,intheRET (Receptortyrosinki nase) gene,thereareinactivatingmutationsiniso latedHD .RETaccountsforupto 2 0 %ofsporadicand…  相似文献   

10.
Introduction Cryptographichashfunctions[1-3]areimportant cryptographicprimitivesandusedinauthentica-tion,non-repudiation,electroniccommerceand encryptionschemes.Cryptographichashfunctions havetosatisfyrequirementsofonewaynessand collisionresistance[4-7].Onesuchfamilyofhash functionsistheMDxfamily.Thisfamilyincludes hashfunctionssuchasMD5,SHA-1and RIPEMD-160.TheMD5hashfunctionwasproposedby Rivest[2].AnattackonMD5waspresentedby Wang[8].Butthedetailofattackalgorithmwasnot discovereduntil…  相似文献   

11.
Objective To study genetic polymorphism of 6 Y chromosomal STR in Hui ethnic group living in Ningxia Hui ethnic autonomous region, in order to evaluate their usefulness in forensic science and enrich the Chinese genetic information resources. Methods We investigated 101 unrelated, healthy, male individuals of Hui ethnic group and studied their allelic frequency distribution and haplotype diversity of 6 Y chromosomal STR. Primer for each loci was labeled with the fluorescent by FAM (blue) or TAMRA(yellow). The data of Hui ethnic group were generated coamplification, GeneScan, genotype, and genetic distribution analysis. Results 31 alleles and 43 phenotype(DYS385) were detected, with the frequencies ranging from 0. 0099- 0. 7129. Out of a total of 101 individuals, 96 showed different haplotypes; 91 were unique; 5 were found 2 times. The haplotype diversity for 6 Y-STR loci was 0. 9990. Conclusion The date obtained can be valuable for individual identification, paternity testing in forensic fields and for population genetics because of 6 Y-STR loci high polymorphism.  相似文献   

12.
甘肃裕固族9个STR基因座遗传多态性研究   总被引:10,自引:0,他引:10  
目的 研究中国甘肃裕固族STR遗传结构。方法 选择 9个STR基因座 (D3S135 8,VWA ,FGA ,TH0 1,TPOX ,CSF1PO ,D5S818,D13S317,D7S82 0 ) ,采用STR复合扩增及荧光标记STR基因扫描技术 ,同时检测 12 0个裕固族健康无关个体血液样本。结果  9个STR基因位点共检出 6 5个等位基因 ,基因频率分布在 0 .0 0 5 7~0 .5 795 ;基因型共有 178种 ,频率分布在 0 .0 114~ 0 .30 6 8之间 ;9个STR位点基因型分布均符合Hardy Weinberg平衡定律 (P >0 .0 5 ) ;9个STR位点多态信息量 (PIC)均大于 0 .6 0 5 4 ,杂合度 (H)均大于 0 .6 15 8,个体识别力 (DP)均大于 0 .82 2 6 ,非父排除率 (EPP)均大于 0 .5 0 17。结论 获得了中国甘肃裕固族 9个STR基因座的遗传多态性数据 ,丰富了中华民族基因数据库 ,在人类群体遗传学及法医学研究领域有重要应用价值。  相似文献   

13.
中华民族STR遗传结构及变化规律的研究(Ⅰ)   总被引:5,自引:3,他引:2  
选择 9种 STR基因位点和 Amelogenin基因位点 ,以测序为基础 ,研究我国汉族人群 STR遗传结构。采用基因自动测序仪建立了 10个位点基因分析方法 ,通过对汉族群体的基因扫描、基因分型和遗传结构分析 ,获得了 STR基因传递特征的大量基因遗传数据 ,在汉族人群 DP为 1.0 5× 10 -10 ,EPP为 0 .9998,为建立我国不同民族 STR基因数据库、基因资源研究与保持奠定了基础 ,为生物考古、基因诊断、性别鉴定、个人识别、司法审判、侦察破案提供有力的科学依据。  相似文献   

14.
目的 获得CSF1P0、TPOX和TH0 1三个短串联重复序列 (shorttandemrepeat ,STR)在新疆哈萨克族人群中等位基因频率、基因型频率及相关法医学数据。方法 应用PCR技术、4 0 g·L-1(4% )变性聚丙烯酰胺凝胶电泳及银染技术对上述三个STR位点分型。结果 新疆哈萨克族人群CSF1P0位点有 8个等位片段 ,TPOX位点有 8个等位片段 ,TH0 1位点有 7个等位片段 ;3个位点的基因型分布均符合Hardy Weinberg平衡 ;各位点杂合度分别为 0 .875 3、0 .8777、0 .932 1,多态信息量分别为 0 .74 0 1、0 .75 6 8、0 .75 0 9。结论 得到的上述三个位点的基因频率数据可为新疆哈萨克人群遗传学研究和法医学应用提供依据  相似文献   

15.
Objective To study the genetic relationship between Kirgiz individuals living in Sinkiang China and analyze the difference among Kirgiz and the other population with STR polymorphisms. Methods PCR amplification was performed using PE9700, the PCR products were typed by automated sequencer and genescan. Results A database of nine STR loci of Kirgiz was established. It shows there are at least 73 STR alleles and 191 genotypes in Kirgiz. Genotype frequencies distribution showed no deviation from Hardy-Weinberg equilibrium by χ^2 -test. Kirgiz was compared with the other Chinese ethnic groups, then the American Black and the White. Conclusion These results suggested that the nine STR loci and Amelogenin locus were very useful in human identification, biological archaeology and gene resource studies.  相似文献   

16.
云南白族STR遗传多态性研究   总被引:4,自引:1,他引:3  
目的 研究我国白族STR遗传多态性。方法 通过STR复合扩增、基因扫描、基因分型调查了 98名中国白族无关个体 1 5个STR基因座等位基因分布情况。结果 共检出 1 3 4个STR等位基因 ,其频率分布在 0 .0 0 5 8~ 0 .5 799之间 ,杂合度 (H)为 0 .5 83 4~ 0 .882 8,个体识别力 (DP)为 0 .773 9~ 0 .9666,非父排除率 (EPP)为 0 .5 692~ 0 .8694,多态信息量 (PIC)为 0 .5 3 1 7~ 0 .8694。结论 为进一步研究中华民族STR遗传结构奠定了基础 ,在人类学、法医学等领域也有重要的应用价值  相似文献   

17.
STRisauniversalgeneticmarkerthathaschangeable polymorphismandstableheredityinhuman genome .ItisaspecificDNAsegmentcomposedof 2~ 7basepairsasitscoresequence ,andisformedthroughtherepeatedconnectionofthesameone[1,2 ] .Sinceithasthecharacteristicssuchasnumerousa…  相似文献   

18.
陕西汉中地区人群15个STR基因座的多态性分析   总被引:5,自引:1,他引:4  
目的 调查 15个STR基因座 (D3S135 8、vWA、FGA、TH0 1、TPOX、CSF1PO、D5S818、D13S317、D7S82 0、D16S5 39、D8S1179、D2 1S11、D18S5 1、D2S1338、D19S4 33)在陕西省汉中地区汉族人群中的多态性分布 ,为群体学研究、法医学个体识别和亲权鉴定提供基础数据。方法 应用AmpF/STRIdentifiler荧光标记复合扩增试剂盒 ,结合ABI310 0Avant遗传分析仪 ,对汉中地区 10 3名汉族无关个体的静脉血进行扩增和电泳检测 ,并利用Genescan和Genotype软件进行自动分型。结果  15个STR基因座在汉中地区汉族人群中的等位基因频率分布在 0 .0 0 4 9~ 0 .5 0 4 9,基因型频率分布在 0 .0 0 97~ 0 .32 0 4 ,累计耦合概率为 5 .5× 10 -17,累计非父排除率为 0 .999999999。结论 我们所应用的 15个STR基因座在陕西汉中地区汉族人群中具有较高的多态性 ,适合于该地区的群体学研究、法医学实践  相似文献   

19.
目的 了解新疆维吾尔族群体 4个STR位点的基因及基因型分布 ,获得 4个基因座的群体遗传学数据。方法 采用PCR扩增技术和基因扫描技术进行样本STR遗传结构分析。并与其他种族、人群的等位基因频率进行比较。结果  4个STR位点在新疆维吾尔族人群中均具有遗传多态性。 4个STR位点的基因型分布均符合Hardy Weinberg平衡定律 (P >0 0 5 )。不同人群基因频率分布存在一定的差异。家系分析显示 :4个STR位点等位基因均按孟德尔遗传定律呈共显性传递。结论 所得到的等位基因频率等数据可为遗传学研究、法医个体识别及亲子鉴定提供依据  相似文献   

20.
中国撒拉族线粒体DNA序列遗传多态性研究   总被引:3,自引:0,他引:3  
目的 以无关个体为对象 ,研究撒拉族人群线粒体DNA(mtDNA)序列遗传多态性。方法 应用PCR扩增产物直接测序法 ,对 10 0名撒拉族无关个体线粒体DNAD 环区高变区Ⅰ (HVSⅠ )进行测序分析。结果 在mtDNAHVSⅠ 16 0 91~ 16 4 18之间与Anderson相应序列比较共发现有 83处突变 ,构成 75种单倍型。点突变的主要形式为碱基替代 ,其中转换 83.5 4 % ,颠换 12 .6 6 % ,碱基插入 1.9% ,缺失 1.7%。撒拉族线粒体DNAHVSⅠ基因差异度为 0 .9912 ,偶合概率为 0 .0 189。结论 撒拉族与其他群体比较有其独特的线粒体DNA序列遗传特点 ,与亚洲其他人种及高加索人有明显差异。线粒体DNA序列多态性在群体遗传学调查及法医学个体识别方面有广泛的应用前景。  相似文献   

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