REGULATION OF PRODUCTION OF PARATHYROID HORMONE－RELATED PEPTIDE （PTHrP） AND EXPRESSION OF ITS mRNA IN A HUMANLIVER－DERIVED CE

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Time-series model for vehicle speeds

This paper presents a time-series model for the spot speeds of vehicles on a road section. Based on time-series analysis techniques, the model incorporates information on the extent of existing dependency between the speeds of successive vehicles. The model for the data is chosen while relying heavily on the data, and thus emphasis is given to their special characteristics. The advantages of using the model are examined with regard to the relative speed of two successive vehicles along a road section. The results are compared with those obtained by using a model of independent observations; fewer errors are obtained with the time-series model. Therefore, it is concluded that the sequence of speed observations contains valuable information which should be incorporated into speed models.     

Information needs of the continuing urban transportation planning process

Urban transportation is identified as a functional element in the broader context of urban facilities and services. From this point of view, the relative merits of separate information systems for transportation planning and general urban planning, as contrasted to unified systems for all urban management functions, are discussed. The overriding need to make the most effective use of urban resources argues strongly for the unification of urban information systems to the greatest possible extent consistent with the special data requirements of various functional programs. The need to identify and correlate data items for very small areal units and to keep current records of the constantly shifting patterns of social and economic activities in urban areas present difficult, but not insurmountable technical problems. However, the most serious barrier to the development and implementation of comprehensive urban information systems is concluded to be institutional, rather than technical, in nature.     

Further evidence on the temporal stability of disaggregate travel demand models

Current evidence on the transferability of disaggregate travel demand models is inconclusive. Adding to this body of research, the present analysis focuses upon the temporal characteristics of work trip behavior in the San Francisco Bay Area. Using before and after data sets associated with the BART Impact Travel Study, multinomial logit models of work trip modal choice are estimated. The results indicate that the general form and the coefficient estimates of a pre BART model are transferable in time. Moreover, when updated to reflect BART's presence, the model's predictive success and its implied elasticity measures are generally accurate, relative to those implied by reestimating the entire model on post BART data. Finally, as economic theory would predict, elasticity measures of the service related variables were found to increase over time.     

An application of variance reduction techniques in freeway simulation

Computer simulation models are used in a variety of applications in transportation engineering and have become a prime aid in decision making. The applications range from evaluating traffic control strategies for single intersections to such complex decision processes as evaluating the impact of removing toll facilities at the George Washington Bridge in New York City. While it is widely accepted that simulation offers an unmatchable capability of evaluating alternate control policies, the high variance of the output variable presents a critical problem in such comparative analyses. The simulation models with high output variance must be run longer or replicated many times to achieve a desired precision level, and that corresponds to increased cost of computer resources. This paper describes and illustrates the application of variance reduction concepts that can improve the reliability and efficiency of the simulation experimental process by taking advantage of the simulation model structure. The two variance reduction concepts (common random numbers and antithetic variates) reduce the variance of the output variable by replacing the original sampling procedure with a new procedure that yields the same expected value but with a smaller variance. The application of the variance reduction concept was illustrated using results from experiments with a freeway simulation model. The results indicate that both common random numbers and antithetic variates sampling procedures appreciably reduce the variance of the simulation output measure.     

Roll Dynamics of Commercial Vehicles

An analytical model is developed here for studying the roll dynamics of commercial vehicles. Large displacements and rotations are accounted for in this nonlinear model so that it can be used for the study of roll dynamics well beyond the limits of wheel lift-off. The model is used to illustrate some of the dynamic phenomena in vehicle rollover, especially the interactive coupling between the roll and the vertical modes of motion. The influence of suspension backlash on rollover resistance is demonstrated, and the phenomenon of roll motion resonance is illustrated to suggest new means for evaluating vehicle rollover sensitivity.     

Comment Some reflections on port competition in the United States and western Europe

'Port competition' is a rather puzzling expression. This paper approaches it literally, searching for precise meanings. In seaports that contain complex and changeable mixtures of public and private enterprise, who competes and why? The answers to these questions are not conclusive but suggestive indications are found in the US, UK and northwestern Europe. Finally, we discuss what seem to be the key influential factors which may impact on the competitiveness of a port.