CT reconstruction with priori MRI images through multi-group datasets expansion

Computed tomography (CT) reconstruction with a well-registered priori magnetic resonance imaging (MRI) image can improve reconstruction results with low-dose CT, because well-registered CT and MRI images have similar structures. However, in clinical settings, the CT image of patients does not always match the priori MRI image because of breathing and movement of patients during CT scanning. To improve the image quality in this case, multi-group datasets expansion is proposed in this paper. In our method, multi-group CT-MRI datasets are formed by expanding CT-MRI datasets. These expanded datasets can also be used by most existing CT-MRI algorithms and improve the reconstructed image quality when the CT image of a patient is not registered with the priori MRI image. In the experiments, we evaluate the performance of the algorithm by using multi-group CT-MRI datasets in several unregistered situations. Experiments show that when the CT and priori MRI images are not registered, the reconstruction results of using multi-group dataset expansion are better than those obtained without using the expansion.     

装配式桩基码头设计建造应用现状与展望

针对水运工程高桩梁板式桩基码头设计建造过程中存在的构件标准化及装配化程度差、施工效率低等问题,分析装配式桩基码头设计建造应用现状,总结装配式桩基码头结构体系的基本特点、模式及连接方式,提出装配化程度指标构件装配率和体积装配率概念,并根据实际工程案例得出传统高桩码头的装配率指标。     

燃气蒸汽式弹射内弹道研究

燃气-蒸汽式弹射方式以其结构简单、温度适中、压力输出平稳等优点,被越来越广泛地应用到水下运载器的发射系统中,深入研究燃气-蒸汽式弹射装置的内流场对弹射装置的设计、改进具有重要意义.本文通过采用3种不同仿真模型对燃气-蒸汽式弹射内弹道进行计算,结果表明:对流场进行仿真计算时应同时引入汽化模型和组分输运模型,其仿真结果与实际情况更为相符.汽化模型对流场温度的影响比对压力和速度的影响更为明显.研究成果可为燃气-蒸汽式弹射装置的设计与改进提供理论支撑.     

城市轨道交通列车控制仿真模型研究

列车运行控制系统的应用,有效地提高了城市轨道交通的运行效率.由于缺乏相关的技术参数,应用传统牵引计算理论方法的列车运行控制仿真系统,若未充分考虑系统控车的特性,在工程应用中控制的精度将无法保证.本文着重考虑信号系统工程设计的限制条件,将列车的加减速性能和速度控制策略作为主要研究对象,构建基于能量守恒原理和信号控制条件的列车速度控制仿真模型.在此基础上设计仿真模型,实现所需要的系统功能结构和仿真流程,并开发形成软件系统.在实际运行线路案例研究中,与采用通用列车运行仿真系统获得的结果比较,验证本文所建仿真模型的精度和工程适用性.     

Reliability Modeling and Maintenance Policy Optimization for Deteriorating System Under Random Shock

Performance degradation and random shock are commonly regarded as two dependent competing risks for system failures. One method based on effective service age is proposed to jointly model the cumulative effect of random shock and system degradation, and the reliability model of degradation system under Nonhomogeneous Poisson processes (NHPP) shocks is derived. Under the assumption that preventive maintenance (PM) is imperfective and the corrective maintenance (CM) is minimal repair, one maintenance policy which combines PM and CM is presented. Moreover, the two decision variables, PM interval and the number of PMs before replacement, are determined by a multi-objective maintenance optimization method which simultaneously maximizes the system availability and minimizes the system long-run expect cost rate. Finally, the performance of the proposed maintenance optimization policy is demonstrated via a numerical example.     

上海市历史城区震后应急救援路网评价与优化

随着我国城市化进程加快,自然灾害问题也日渐凸显,作为主要自然灾害之一的地震正在严重影响着我国城市的公共安全.城市交通系统是城市重要的生命线,因此研究震后城市应急救援道路网络连通可靠度具有重要的现实意义.历史城区由于其建筑多为老旧平房,抗震性能差,而且城区道路空间局促,在遭遇地震时路网更易堵塞.本文以上海豫园区域路网为例,基于瓦砾堆积模型对震后路段通行概率进行计算,采用蒙特卡洛模拟方法对路网节点连接可靠度进行计算,对震后路网路段单元和节点的可靠性进行评估,并在此基础上判别关键路段和优化应急医疗救援路径.     

Novel experimental strategy for high resolution AFM imaging of membrane-associated bacterial toxins

Bacterial pore-forming toxins （PFTs） are essential virulence factors of many human pathogens. Knowl- edge of their structure within the membrane is critical for an understanding of their function in pathogenesis and for the development of useful therapy. Atomic force microscopy （AFM） has often been employed to structurally interrogate many membrane proteins, including PFTs, owing to its ability to produce sub-nanometer resolution images of samples under aqueous solution. However, an absolute prerequisite for AFM studies is that the samples are single-layered and closely-packed, which is frequently challenging with PFTs. Here, using the prototypical member of the cholesterol-dependent cytolysin family of PFTs, perfringolysin O （PFO）, as a test sample, we have developed a simple, highly robust method that routinely produces clean, closely-packed samples across the entire specimen surface. In this approach, we first use a small Teflon well to prepare the supported lipid bilayer, remove the sample from the well, and then directly apply the proteins to the bilayer. For reasons that are not clear, bilayer preparation in the Teflon well is essential. We anticipate that this simple method will prove widely useful for the preparation of similar samples, and thereby enable AFM imaging of the greatest range of bacterial PFTs to the highest possible resolution.     

米思米软件在模具工业中应用的可行性分析

本文介绍了米思米软件的创立以及三大功能,分析了该软件的优越性,得出作为标准件的全球性软件,在企业中米思米软件可以缩短设计时间,提高采购部门的效率,最终缩短整个从设计到制作的时间;在教学中米思米软件可以提高学生学习兴趣,巩固理论知识,强化实践操作,其应用前景非常广阔。     

小直径盾构施工中管片纵向应力监测研究

为了探索小直径盾构法隧道在施工过程中管片纵向应力的变化规律,对北京槐房再生水厂污水隧道管片纵向应力进行了现场监测:将第976环、第1 054环管片分别设为第1和第2监测断面,2监测断面各预埋5个纵向应力计,各监测断面从本监测断面管片安装后即开始监测,当盾构掘进至第1 129环时停止监测。研究表明:1)在管片离开盾尾50环后,其纵向应力波动值小于管片拼装期间应力值的5%。2)在盾构掘进期间,管片距离盾构越远,其纵向压应力值越小。3)在管片拼装期间,管片距离盾构越远,其纵向压应力经历了先增大后减小的过程。4)管片距离盾构108环后,该管片纵向压应力趋近于0.2~0.3 MPa。5)随着盾构推进,管片纵向应力经历了4个阶段的变化过程,即周期性剧烈波动阶段—动态稳定阶段—逐渐衰减阶段—趋于稳定阶段。     

乙醇汽油对车辆颗粒物排放的影响

在符合国Ⅰ、国Ⅲ、国Ⅴ标准的3辆试验车上,分别燃用国Ⅴ汽油、低芳烃E10、低烯烃E10 3种燃料,进行了NEDC和WLTC工况下的常温冷起动排放试验,重点对颗粒物(PM)排放量和粒子数量(PN)进行分析。结果表明:在两种工况下,燃用乙醇汽油相比普通汽油能大幅降低车辆的PM排放,低芳烃E10对国Ⅰ和国Ⅲ车辆PM降低效果最明显,分别下降19%和35%,低烯烃E10对国Ⅴ车辆PM降低效果最好,下降46%;在WLTC工况下燃用乙醇汽油能大幅降低车辆PN排放,其中低芳烃E10平均降低43%,低烯烃E10平均降低32%。