视屏显示终端作业人员职业应激及心身状态

进行了VDT作业人员职业应激及心身状态的调查研究。结果初步显示VDT作业本身独特的职业性质、工作环境和作业需求形成了VDT作业的主要应激源,其作业时间和作业负荷较大者产生了较高的职业性紧张度。VDT作业人员对工作满意程度较差。心理健康水平评价显示该作业人员心理健康水平较对照人员为低,尤其表现在强迫和抑郁两个心理因子方面。心身疾患评价提示VDT作业可能会给作业人员带来一定的心理—生理障碍。本研究尚未发现VDT对作业人员植物神经功能的不良影响。     

Study on the toxic effect of the mixture of organophosphorus pesticide on perinatal rats

Objective To observe the toxic effect of the mixture of organophosphorus pesticide （MOP） on maternal rats and on the growth and development of their offspring. Methods Totally 40 Sprague-Dawley pregnant rats were randomly divided into three MOP dose groups and one control to which their offspring would be assigned, The experimental dosage of MOP and distilled water were administered orally starting on gestation day 15 and continued for 35 days. The physical development indices and the learning ability of F1 rats were measured during lactation. The pathological changes of uterus and liver of F0 rats were observed after weaning, while the weight ratio of uterus and some viscera to body of the F1 were examined. Results There were obvious changes of uterus and liver in the high-dose group of F0. The body-weight accretion of the F1 in high-dose group was obviously lower than that in control group （P〈0.05）. Some of the MOP F1 rats development indices delayed significantly （P〈 0. 05）, the learning ability decreased obviously, and the time of setting up memory prolonged （P〈0.05）. The ratio of the uterus weight to bodyweight in the F1 MOP groups was significantly higher than that in control group （P〈0. 05）. Oonclusion The experiment doses of MOP are proved to have significant reproductive toxicity on perinatai rats.     

视屏作业人员心理健康水平及个性特征

本文对部分视屏显示终端（ＶＤＴ）操作人员的心理健康水平及个性特征进行研究。结果显示ＶＤＴ作业人员总体心理健康水平较对照组低，强迫和抑郁两个因子分表现更明显。长期从事ＶＤＴ作业者，个性多偏内倾，情绪不稳定。工作满意程度较差。ＶＤＴ作业的职业性紧张程度较高，此因素可能会对工作人员的心理健康产生一定的影响。     

淫羊藿提取物的雌激素样作用研究

目的 评价淫羊藿提取物的雌激素样作用.方法 采用小鼠子宫增重实验、雌激素受体阳性细胞系(MCF-7)细胞增殖及拮抗实验,评价淫羊藿及淫羊藿苷的雌激素样作用及其可能机制.结果 与阴性对照组比较,淫羊藿及淫羊藿苷能使子宫系数由0.097±0.008明显增加至0.156±0.018及0.152±0.016,且用药前、后动物体重由(18.9±1.3)g分别增至(19.8±1.3)g及(20.03±1.3)g,增幅明显高于阴性对照组(P<0.05);淫羊藿苷可使血清雌激素E2由(132.22±11.45)ng/L增高至(147.73±12.43)ng/L,FSH水平由(50.15±3.36)μg/L降低至(44.47±2.46)μg/L(P<0.05),但淫羊藿组雌激素E2水平无明显改变;在24、48、72 h,淫羊藿及淫羊藿苷对MCF-7细胞的增殖均有明显的促进作用(P<0.05),分别由0.238±0.043、0.387±0.051、0.563±0.083增至0.362±0.045、0.521±0.046、0.648±0.043及0.324±0.043、0.465±0.034、0.622±0.079;72 h加入ICI后,细胞增殖明显受到抑制,细胞增值率分别降至99.461%、94.434%.结论 淫羊藿及淫羊藿苷具有雌激素样作用,且其促细胞增殖作用可能是通过雌激素受体(ER)介导产生的.     

关于120阀密封性能的探讨

本文根据密封原理和密封装置及系统设计的基本要求，阐述了１２０ 阀结合部发生漏泄的主要原因，并提出了具体改进措施