三轴应力下黏性土的微结构及其演化规律

利用河海大学自行研制的岩土材料微细结构光学测试系统,进行三轴应力下黏性土微结构特征参数的定量分析,研究三轴应力作用下黏性土微结构的演化规律及其力学特性。研究结果表明:重塑黏性土样在围压较低时,以均匀性破坏为主,局部化变形破坏为辅;荷载作用下,颗粒或孔隙的聚合和崩解同时发生,没有那种过程占据明显的优势;压缩过程中,颗粒所占面积增加,孔隙所占面积减小;颗粒的初始扁圆度越高,压缩过程中颗粒圆度值降低幅度越大,颗粒形状变化也越明显;随着制样含水量的提高,颗粒圆度不断增大,其空间排列变得紧密;随着具有微膨胀特性的黏性土含水量的增加,土体的强度显著下降,加载后的应变率增大。     

千寻位置在江乌航道测量中的应用

航道测量范围大、距离长并且跨省区,但CORS系统测量不能跨省区。针对这一问题,论述了RTK测量、CORS系统测量和千寻位置的定位导航技术。千寻知寸测量方法具有厘米级定位精度,覆盖范围全、无缝衔接、整体精度高,能满足大范围、长距离和跨省区航道测量要求,为类似工程测量提供了一种新方法。     

基于新型冠状病毒传播机理的交通出行易感度研究

为科学判断各交通方式出行过程中人群感染病毒的风险概率进而有效控制病毒传播，借助空气传染病模型，根据已发布的新型冠状病毒传播机理，构建了交通出行的病毒易感度评估模型，模型包含对病毒传播有重要影响的通风、载客密度、暴露时间等主要参数。选用各种运输方式中有代表性的运载工具进行不同假设情景下的易感度评估，结果表明，在各种有效防控措施均得以采用的情景下，乘坐交通工具的易感度相比高危情景降低97%以上，相比基准情景降低93%以上。研究可为交通领域的科学防疫、精准施策提供依据。     

混合式教学视域下高职专业核心课程教学团队的构建

混合式教学的顺利开展和目标达成,有赖于构建技能全面、分工合作的课程教学团队。基于混合式教学对课程教学团队带来的挑战,在分析高职院校专业核心课程教学团队建设现状及所存在弊端的基础上,以《单片机技术与应用》课程教学团队的构建为例,论述了高职院校专业核心课程混合式教学团队构建应遵循的主要原则,以及混合式教学团队构建的基本路径。     

带干扰的多险种再保险的风险模型

由于保险公司的经营规模不断扩大,险种类型不断增多,考虑到用单一险种的风险模型描述风险经营业务的局限性,推广了经典的复合泊松风险模型,讨论了带干扰的多险种再保险风险模型,得到了初始资本为u的破产概率ψ(u)的表达式及伦德伯格不等式。     

5-氮胞苷对宫颈癌细胞系DAPK1异常甲基化的影响

目的　观察宫颈癌细胞系SiHa及HeLa中凋亡相关蛋白激酶 1(DAPK1)的表达与甲基化修饰之间的相关性,以及5 氮胞苷对细胞DAPK1表达和生长的影响。方法　应用甲基化特异性PCR法分析细胞中DAPK1的甲基化状态;采用RT- PCR及免疫组化SABC法检测不同浓度 5- 氮胞苷干预对宫颈癌细胞 DAPK1 mRNA及蛋白表达的影响;MTT法观察5 -氮胞苷对细胞增殖的影响。结果　DAPK1基因在宫颈癌细胞 SiHa中有甲基化修饰,5- 氮胞苷干预能使其甲基化的DAPK1基因重新表达并抑制细胞生长。结论　DAPK1 的甲基化修饰是宫颈癌发生重要机制之一,5 -氮胞苷能使甲基化的DAPK1去除甲基化修饰,重新表达并恢复抑癌作用。     

Geometric Nonlinear Formulation for a Rectangular Plate with Large Deformation

Absolute nodal coordinate formulation for a rectangular plate with large deformation was improved. Based on nonlinear elastic theory, a precise strain expression is used to derive the equations of motion. Both shear strain and transverse normal strain are taken into account. Different from the previous absolute nodal coordinate formulation, the absolute nodal coordinates, which describe the displacement and slope of the element nodes, are separated into three parts: the absolute nodal coordinates in X, Y and Z directions, respectively, so that the dimension of the mass, stiffness and force matrices is reduced. Furthermore, by using constant matrices, which can be calculated and saved before simulation, the nonlinear stiffness matrices can be calculated by matrix multiplication for each time step, so that the computational efficiency can be improved. Finally, simulation example of a rectangular plate with large deformation was used to verify the accuracy and efficiency of the present formulation.     

Five-axis interpolation of continuous short linear trajectories for 3[PP]S-<Emphasis Type="Italic">XY</Emphasis> hybrid mechanism by dual Bezier blending

A novel five-axis real-time interpolation algorithm for 3[PP]S-XY hybrid mechanism is proposed in this paper. In the algorithm, the five-axis tool path for controlling this hybrid mechanism is separated into two sub-paths. One sub-path describes the movement of 3[PP]S parallel kinematic mechanism module, and the other one describes the movement of XY platform. A pair of cubic Bezier curves is employed to smooth the corners in those two sub-paths. Based on the homogenous Jacobian matrix of 3[PP]S mechanism, a relationship between the position errors of every driving joint in hybrid mechanism and the position deviation of the tool tip center point at the moving platform is established. This relationship is used to estimate the approximation error for the corners smoothing according to the accuracy requirement of tool tip center in interpolation. Due to the high computational efficiency of this corner smoothing method, it is integrated into the look-ahead module of computer numerical control (CNC) system to perform online tool path smoothing. By performing the speed planning based on a floating window scheme, a jerk limited S-shape speed profile can be generated efficiently. On this basis, a realtime look-ahead scheme, which is comprised of path-smoothing and feedrate scheduling, is developed to acquire a speed profile with smooth acceleration. A monotonic cubic spline is employed for synchronization between those two smoothed sub-paths in tool path interpolation. This interpolation algorithm has been integrated into our own developed CNC system to control a 3PRS-XY experimental instrument (P, R and S standing for prismatic, revolute and spherical, respectively). A club shaped trajectory is adopted to verify the smoothness and efficiency of the five-axis interpolator for hybrid mechanism control.     

CRC通用校验测试工具的设计与实现

CRC(循环冗余校验码)编码是数字信号传输中用得较普遍的一种差错控制编码.它不但可以用于纠正独立的随机错误,也可以用于纠正突发错误.目前已有的CRC校验算法程序很多,但往往只以一种生成多项式为例进行编写,缺少完整、通用性好、用户界面良好的应用软件.介绍了一种CRC通用校验测试工具的设计与实现过程,本测试工具将各种类型的CRC校验算法进行汇总,类型全、计算精度高、速度快、用户界面好、易操作.     

不同营养饲料加氟喂养大鼠的氟骨症X线观察

目的　观察不同营养饲料加氟喂养大鼠的氟骨症X线表现。方法　用健康 40d龄SD大鼠 ,随机分为对照组、低营养组和富营养组 ,两个实验组大鼠饮含F-4 0mg·L-1单蒸水 ,实验期为 17.5个月 ,检测血氟、尿氟、骨氟及尿羟脯氨酸 (hypro)含量 ,取左髂骨、股骨及胫腓骨拍钼钯片 ,在解剖显微镜下比较观察。 结果　低营养组 (16例 )髂骨及胫骨均有氟骨症X线表现 ,1例比较轻微。富营养组 (10例 )髂骨及胫骨X线表现 :5例骨结构接近正常 ,1例氟骨症可疑 ,4例为氟骨症。实验组血清F-、尿F-、骨F-和尿Hypro明显高于对照组。结论　低营养饲料加重了氟骨症的改变。