柏家沟中桥加宽改造工程

介绍柏家沟中桥原状及有关情况,分析病害缘由,提出改造方案,通过经济比较,确定加宽改造,改善了车辆荷载的通行能力。     

美国限速制定方法及启示

为使我国道路限速的制定更为合理,借鉴国外相关经验是必不可少的。总结了美国设置限速时考虑的主要因素、限速设置方法及其适用条件。对美国部分城市的州际道路及主干路的限速实施状况进行了分析,认为测速相机等自动执法设备的辅助使用能够在很大程度上提高驾驶人对限速的遵守程度。在借鉴美国限速方法及实施经验的基础上,指出我国在制定道路相关限速标准时,应结合国情确定限制速度与运行速度、设计速度之间的互动关系,以及限速与安全、执法等之间的关系。然后针对不同的道路类型、等级等特性研究采用不同的限速方案,解决速度区限速取值及不同速度区之间如何平滑过渡衔接等问题,明确了我国限速研究的基础性内容。     

Sensitivity analysis of parameters for multi-stand roll forming using a new booting model

Multi-stand roll forming is a process that has very complicated deformation behaviour and shows significant nonlinearity.In this paper, the sensitivity analysis of parameters for multi-stand roll forming was performed via a new booting finite element method(FEM) model.Compared with the most of simulation, the new model is more consistent with production process and can account for the effects of roll rotating speed.Based on the model, the process of an open section channel formed with 10 passes was simulated and the sensitivity analysis was conducted with orthogonal experiment design combined FEM model.The multi-stand roll forming process can be efficiently analyzed by the new booting model.And sensitivity analysis shows the hardening exponent plays an important role in controlling the quality of the products.     

浅谈软土泥沼地基的处理方法

介绍了软土及泥沼地基处理方法,有换土垫层法、强夯法、侧向约束法、土工织物加固法、排水固结法、综合处理方法的机理和适用范围。     

浅谈SEAM沥青混合料的施工工艺

介绍SEAM粒料的掺配方法、掺配比例的确定和SEAM沥青混合料的施工工艺。     

关于双箱变截面连续性箱梁的施工

通过实际施工。简单的归纳一下双箱变截面连续箱梁的施工工艺及基本作业方法。     

柴油机高压共轨电控燃油喷射技术

简要介绍柴油机电控高压共轨喷射系统的发展现状,主要分析柴油机电控高压共轨喷射系统的结构和原理,分析了柴油机电控高压共轨喷射系统的关键技术。     

采用变化基本体的授课方法以提高教学效果

在《机械（工程）制图》教学中,学生对基本体的变化及其在实际中的应用难以理解,文中介绍提高基本体教学效果的方法。     

互通立交平面线形设计的经验探讨

通过设计工作的实践,探讨互通立交平面线形设计的具体步骤、操作方法和注意事项,并对匝道线元参数的取值、线元参数与运行速度的关系、线形设计的连续性与协调性等方面提出了一些见解。     

Role of candesartan against cerebral ischemia and oxidative damage in normotensive rats

Objective Angiotensin Ⅱ (Ang Ⅱ ) contributes to modulating blood pressure by stimulation of Ang Ⅱ AT1 receptors. We devised a rat transient middle cerebral artery occlusion (MCAO) model to assess whether oxidative damage is decreased after pretreatment with Angiotensin Ⅱ AT1 receptor blocker (ARB). Methods After 2 weeks pretreatment with ARB 0. 5 and 1 mg/kg, the male Wister rats were subjected to 2 h middle cerebral artery occlusion (MCAO). At 24 h, the lumen diameter of middle cerebral artery, the plasma level of 8-hydroxy-2'-deoxyguanosine (8-OHdG), and HIF-1 a levels were recorded and compared. Results After pretrcatment with ARB 0.5 and 1 mg/kg, blood pressure did not significantly change compared with that of controls. In the group of candesartan at 1 mg/(kg· day), the lumen diameter was significantly increased compared to that in control group [(86.0±5.0) μm vs. (69.0± 2.1) μm; P<0. 01, n = 6- 8]. The plasma 8-OHdG levels of ARB pretreatment groups were decreased. In immunohistochemical findings, 8-OHdG- and HIF-1α-containing cells in ARB pretreatment groups were decreased. Conclusion Brain ischemia and oxidative damage can be reversed by AT1 receptor blockade in normotensive rats after transient cerebral artery occlusion.