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尽管癌症治疗在过去的十多年取得了显著进展,但肿瘤学仍属于目前最不能满足临床需要的学科领域。在过去十多年里,临床药理学的进步和研发活动方面的巨大投资使得“癌症治疗”发展为“治疗过程研究”的数量急剧增加。但事实上,癌症和其他慢性疾病一样,治疗效果都很差,由此很多大型医药公司和生物制药公司都比以往更大力度的投入资金,用于肿瘤学和其他强效候选药物的研发上。[第一段]  相似文献   
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1空气悬架发展的简史 空气弹簧发明于100年前,它的雏形是马车上使用的皮囊。直到20世纪30年代出现的纤维叠层橡胶制作技术才使制造实用的空气弹簧成为可能。人们首先考虑在客车上应用空气弹簧。  相似文献   
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The Intergovernmental Panel on Climate Change reports that rising seas by the end of this century will increase the severity of coastal flooding and erosion. The Caribbean region is home to many small islands that are vulnerable to sea level rise and storm surge. Much of the literature examining impacts of sea level rise in the Caribbean focuses on ecosystems, infrastructure, and recreation. Few studies have examined how sea level rise will impact historic and culturally important places. In an effort to address this research gap, geographic information systems and crowd-sourced, georeferenced photographs were used to build a first-of-its-kind database of 542 Caribbean small island cemeteries. Vulnerable cemeteries were then identified based upon elevation, proximity to the ocean, and the coastal profile. Over one-fifth of the cemeteries surveyed are within 100 m of the coast. The highest concentrations of vulnerable cemeteries are on flat islands such as the Cayman Islands. Yet, some mountainous islands such as Saint Martin also have potentially vulnerable cemeteries. These findings suggest that the bereaved, cemetery managers, and managers of coastal areas that have cemeteries may have additional considerations when making long-term decisions about where and how to bury the deceased.  相似文献   
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Via a conventional steering system the driver perceives desired and disturbing effects such as road feedback and resonance effects, respectively. They appear with overlapping frequency spectra within the driver's steering torque. This paper introduces a control algorithm that is suppressing periodic disturbances without affecting useful steering road feedback attributes as well as regular power assistance characteristic. This is realised by an integrated torque actuator within the steering column in conjunction with a conventional Hydraulic-assisted Power Steering (HPS) system.  相似文献   
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