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新生猪胰岛细胞培养移植实验
引用本文:苟寒梅,王惠芳,姜薇,徐利,高慧.新生猪胰岛细胞培养移植实验[J].西安交通大学学报(医学版),1992(1).
作者姓名:苟寒梅  王惠芳  姜薇  徐利  高慧
作者单位:西安医科大学第一附属医院内分泌代谢病研究室,西安医科大学第一附属医院内分泌代谢病研究室,西安医科大学第一附属医院内分泌代谢病研究室,西安医科大学第一附属医院内分泌代谢病研究室,西安医科大学第一附属医院内分泌代谢病研究室 西安 710061,西安 710061,西安 710061,西安 710061,西安 710061
摘    要:本文报道了经Ham F_(10)培养的新生猪胰岛细胞功能状况及其植入Sprdgue-Dawley鼠体内后移植物成活情况,并观察了甘草对移植物的影响.其方法是将已培养的新生猪胰岛细胞移植到4组大鼠的腹腔大网膜(第1、2组)肾包膜(第3组)及脑组织(第4组),第1组饮用甘草水、术后8周~11周切除移植物送病理检查,结果显示第1、2组移植物成活可达11周之久,且以饮用甘草水者更好。本实验的目的是寻找来源较广的异种胰腺组织供体。

关 键 词:  胰岛细胞培养  移植  大白鼠  甘草

EXPERIMENTAL OBSERVATION OF TRANSPLANTATION OF CULTURED NEWBORN PIG PANCREATIC ISLET CELLS
Gou Hanmei,Wang Huifang Jiang Wei,et al.EXPERIMENTAL OBSERVATION OF TRANSPLANTATION OF CULTURED NEWBORN PIG PANCREATIC ISLET CELLS[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1992(1).
Authors:Gou Hanmei  Wang Huifang Jiang Wei  
Abstract:In this article, we report the pancreatic islet cells function of newborn pig pancreatic tissues cultured by Ham F_(10), and the condition of graft survived into the bodies of Sprague-Dawley rats, and also study the influence of Glycyrrhiza uralensis to the grafts. The cultured islet cells of newborn pig were transplanted into the mesenteric cavities (the first & second group), kidney cystic(the third group) and brain tissucs (the fourth group) of the 4 groups adult Sprague-Dawley rats. The first group rats drank Glycyrrhiza uralensis water, after 8~11weeks of operation a examination pathological was made with the cut graft The results showed that the first and second group grafts survived over 11weeks, and survived better the group drunk the Glycyrrhiza uralensis water was much better than other. The purpose of this experiment is to find the heteropolar source of pancreatic tissues offering body.
Keywords:pig  pancreatic islet cells cultured  transplantation  Sprague-Dawley rat  Glycyrrhiza uralensis
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