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| 兔肾VX2移植瘤模型的建立及其超声显像检测 | |
| 引用本文： | 王子明,佘军军,程伟,李小鹏,李谦,车向明,韩水平,白卓亚.兔肾VX2移植瘤模型的建立及其超声显像检测[J].西安交通大学学报(医学版),2006,27(1):55-58. |
| 作者姓名： | 王子明 佘军军 程伟 李小鹏 李谦 车向明 韩水平 白卓亚 |
| 作者单位： | 1. 西安交通大学医学院第二附属医院泌尿外科,陕西,西安,710061 2. 西安交通大学医学院第一附属医院普外科,陕西,西安,710061 3. 西安交通大学医学院第二附属医院超声科,陕西,西安,710061 4. 西安交通大学医学院病理学教研室,陕西,西安,710061 5. 武功县医院,陕西,武功,712200 |
| 基金项目： | 国家自然科学基金资助项目(No.30371831) |
| 摘 要： | 目的比较建立兔肾VX2移植瘤模型的不同方法的优劣。方法分别用瘤液穿刺法、瘤块液种植法、瘤块包埋法建立兔肾VX2癌模型。采用超声技术动态检测肿瘤体积及CDFI的变化,确定该模型最佳实验干预时段及其血流参数范围。比较各自的成瘤率;观测肾脏肿瘤的大小及其回声、瘤内血管生成以及血流阻抗等指标。结果瘤块包埋法可建立稳定的兔肾VX2移植瘤模型。B超可以实时、准确、方便的监测肿瘤体积及血流动力学变化。结论兔肾VX2移植瘤是一种造模方法简便且成瘤率高的肾癌动物模型,采用超声技术能精确、无创的动态监测肿瘤体积变化及血流特征。 |
| 关 键 词： | 兔 VX2肾癌 超声技术 |
| 文章编号： | 1671-8259(2006)01-0055-04 |
| 收稿时间： | 2005-08-26 |
| 修稿时间： | 2005-09-04 |
Establishing rabbit VX2 carcinoma model and monitoring it with color Doppler energy ultra sound technique |
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| Wang Ziming,She Junjun,Cheng Wei,Li Xiaopeng,Li Qian,Che Xiangming,Han Shuiping,Bai Zhuoya.Establishing rabbit VX2 carcinoma model and monitoring it with color Doppler energy ultra sound technique[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2006,27(1):55-58. | |
| Authors: | Wang Ziming She Junjun Cheng Wei Li Xiaopeng Li Qian Che Xiangming Han Shuiping Bai Zhuoya |
| Abstract: | Objective To compare the advantages and disadvantages of several methods to establish the rabbit VX2 carcinoma model.Methods Ultrasound technique was used to confirm the best periods of experiment on the rabbit VX2 carcinoma mode.The rabbit VX2 carcinoma model was established by different ways,such as tumor cells fluids and tumor block transplanting guided by B-ultrasound,tumor block transplanting by operation to compare their successful rate.Kidney size and other indexs were observed.Results Tumor block transplanting by operation was the most successful to establish a steady model.Conclusion The rabbit VX2 carcinoma is one of the biggest animal models for kidney carcinoma's experimental research;it is steady and easy to be manipulated. |
| Keywords: | rabbit VX2 kindey carcinoma B ultrasound |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |