| SCC-Ag、CEA在肺癌患者血清中的表达及临床意义 |
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| 引用本文： | 刘晓玲,汪涛,王雯,姜缨,郑伟.SCC-Ag、CEA在肺癌患者血清中的表达及临床意义[J].西安交通大学学报(医学版),2004,25(5):468-469,516. |
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| 作者姓名： | 刘晓玲 汪涛 王雯 姜缨 郑伟 |
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| 作者单位： | 西安交通大学第一医院放疗科,陕西西安,710061 |
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| 摘 要： | 目的 探讨肺癌患者治疗前后血清鳞状细胞癌抗原 (SCC Ag)和癌胚抗原 (CEA)的表达及临床意义。方法 利用全自动快速粒子酶免疫分析系统 (IMX) ,检测 134例肺癌患者治疗前后血清SCC Ag和CEA的水平 ,分析SCC Ag和CEA检测值与肺癌临床病理特征之间的关系。结果 肺癌患者治疗前血清SCC Ag、CEA升高与肿瘤病理学类型和临床分期呈正相关 (P <0 .0 5 ) ,联合检测可以提高肺癌诊断的阳性率。结论 血清SCC Ag、CEA检测可用于肺癌的辅助诊断以及对病期和预后的判断。
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| 关 键 词： | 肺癌 鳞状细胞癌抗原 癌胚抗原 |
| 文章编号： | 1671-8259(2004)05-0468-02 |
Expression of SCC-Ag and CEA and its clinical significance in patients with lung cancer |
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| Liu Xiaoling,Wang Tao,Wang Wen,Jiang Ying,Zheng Wei.Expression of SCC-Ag and CEA and its clinical significance in patients with lung cancer[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2004,25(5):468-469,516. |
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| Authors: | Liu Xiaoling Wang Tao Wang Wen Jiang Ying Zheng Wei |
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| Abstract: | Objective To investigate the ex pr ession of squamous cell carcinoma antigen (SCC-Ag) and carcinoembryanic antigen (CEA) and its clinical significance in patients with lung cancer. Meth ods The pre-treatment serum from 134 patients with lung cancer from 1998 to 2002 were analyzed for the SCC-Ag level and CEA level by IMX, and the correlation of the SCC-Ag level and CEA level with the clinicopathologic charac teristics were also detected. Results Significant correlations were found between the pre -treatment SCC-Ag level, and CEA level and the pathologic classification, clin ical stage, the positive rate of diagnosing lung cancer was raised by combined a ssay with serum SCC-Ag and CEA. Conclusion Pre-treatment and after-treatment measurement of serum SCC-Ag level and CEA level can be used for diagnosis, prediction of pr ognosis and monitor of after-treatment recurrence in patients with lung cancer. |
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| Keywords: | lung cancer squamous cell carcinoma antigen (SC C-Ag) carcinoembryanic antigen (CEA) |
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