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恶性滋养细胞肿瘤致子宫穿孔26例临床分析
引用本文:崔丽侠,张思真.恶性滋养细胞肿瘤致子宫穿孔26例临床分析[J].西安交通大学学报(医学版),1996(1).
作者姓名:崔丽侠  张思真
作者单位:西安妇幼系妇女保健学教研室,西安第一附属医院妇产科教研室
摘    要:1957~1987年我院共收治恶性滋养细胞肿瘤342例,发生子宫穿孔26例。其中绒毛膜癌147例,穿孔者16例,占10.9%;侵蚀性葡萄胎195例,穿孔10例,占5.1%。其主要症状为阴道流血、阵发性腹痛或腹部剧痛,下腹部有压痛、反跳痛及移动性浊音。21例行急诊手术,术后3天开始化疗。死亡3例,均系绒癌Ⅳ期患者。23例经手术加化疗后治愈。

关 键 词:绒毛膜癌  侵蚀性葡萄胎  子宫穿孔

PERFORATION OF UTERUS IN MALIGNANT TROPHOBLASTIC TUMOR:CLINICAL ANALYSIS OF 26CASES
Cui Lixia, Zhang Sizhen.PERFORATION OF UTERUS IN MALIGNANT TROPHOBLASTIC TUMOR:CLINICAL ANALYSIS OF 26CASES[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1996(1).
Authors:Cui Lixia  Zhang Sizhen
Abstract:patients with malignant trophoblastic tumor were treated in our hospital during the period of 1957 to 1987.Of thern, 147 were diagnosed as Chofiocarcinoma and 195 as invasivvmole. In total,26 patients(7.6%)suffering from perforation of uterus.16 of them were patients with cbotiocinoma and 10 were patients with invasivemole. The clinical characters of peforation of uterus included vaginal bleeding,paroxysmal abdominal pain,tenderness and rebound tenderness on the lower abdomen,abdofninal shifting dullness. 25 were diagnosed before operation and one was misdiagnosed as ectopic pregnancy.All of the patients were treated by operation and chemotherapy. 23 were cured and 3 cases died of exhaustion and/or brain metastasis.
Keywords:Perforation of the uterus  invasive mole  choriocarcinoma
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