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梧桐子的降压作用
引用本文:邱培伦,王美纳,邓秀玲,李振富,杨亚惠,李宝棣,王玉琦,程洪生,何善民.梧桐子的降压作用[J].西安交通大学学报(医学版),1984(3).
作者姓名:邱培伦  王美纳  邓秀玲  李振富  杨亚惠  李宝棣  王玉琦  程洪生  何善民
作者单位:西安医学院药理教研室,西安医学院药理教研室,西安医学院药理教研室,西安医学院第一附属医院,西安医学院第一附属医院,西安医学院第一附属医院,西安医学院第一附属医院,陕西省卫生干部进修学院,陕西省卫生干部进修学院
摘    要:动物实验和部分病人的临床观察表明,梧桐子具有温和的降压作用,其作用机制可能与其抑制胆碱酯酶作用有关。

关 键 词:种子  生物碱  降压作用  胆碱酯酶

Hypotensive Action of the Seeds of Chinese Parasoltree(SCP)
Qiu Peilun et al.Hypotensive Action of the Seeds of Chinese Parasoltree(SCP)[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1984(3).
Authors:Qiu Peilun
Abstract:Total alkaloid of SCP was given intravenously to rabbits, dogs and cats (0.3g/kg, corresponding to crude drugs ), and a mild hypotensive action was produced immediately. Their blood pressure was decreased 26.27%, 29.23% and 31.76% respectively. SCP extract was administered to 32 patients with nosebleed, 90g(corresponding to crude drugs)three times daily. Six days later, hypotensive action occurred in 25 patients, and average diastolic and systolic pressure dropped 11.16 and 7.16mmHg respectively. The results suggest that the mechanism of hypotensive action of SCP is related to depression of acetylcholine esterase.
Keywords:Seeds  Alkaloid  Hypotensive action  Acetylcholine
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