| IMMUNOHISTOCHEMICAL LOCALIZATION OF EPIDERMAL GROWTH FACTOR RECEPTOR AND C－erbB－2 ONCOGENE PRODUCT IN DEVELOPING HUMAN PLACEN |
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| 引用本文： | 马军,王作清,苏宝山,张建国.IMMUNOHISTOCHEMICAL LOCALIZATION OF EPIDERMAL GROWTH FACTOR RECEPTOR AND C－erbB－2 ONCOGENE PRODUCT IN DEVELOPING HUMAN PLACEN[J].西安交通大学学报(英文版),1996(1). |
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| 作者姓名： | 马军 王作清 苏宝山 张建国 |
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| 作者单位： | Department of Obstetrics and Gynecology，First Affiliated Hospital，Xi'an Medical University，Xi'an 71004 |
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| 摘 要： | ＩＭＭＵＮＯＨＩＳＴＯＣＨＥＭＩＣＡＬＬＯＣＡＬＩＺＡＴＩＯＮＯＦＥＰＩＤＥＲＭＡＬＧＲＯＷＴＨＦＡＣＴＯＲＲＥＣＥＰＴＯＲＡＮＤＣ－ｅｒｂＢ－２ＯＮＣＯＧＥＮＥＰＲＯＤＵＣＴＩＮＤＥＶＥＬＯＰＩＮＧＨＵＭＡＮＰＬＡＣＥＮＴＡ（马军）（王作清）（苏宝...
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IMMUNOHISTOCHEMICAL LOCALIZATION OF EPIDERMAL GROWTH FACTOR RECEPTOR AND C-erbB-2 ONCOGENE PRODUCT IN DEVELOPING HUMAN PLACENTA |
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| Ma Jun,Wang Zuoqing,Su Baoshan,Zhang Jianguo.IMMUNOHISTOCHEMICAL LOCALIZATION OF EPIDERMAL GROWTH FACTOR RECEPTOR AND C-erbB-2 ONCOGENE PRODUCT IN DEVELOPING HUMAN PLACENTA[J].Academic Journal of Xi’an Jiaotong University,1996(1). |
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| Authors: | Ma Jun Wang Zuoqing Su Baoshan Zhang Jianguo |
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| Abstract: | Cytologic locailzation of epidermai growth factor receptor (EGF-R) and C-erbB2oncogene product in normal developing placenta ovas studied by avidin/biotin immunoperoxidase techniques.Both proteins were predominantly expressed in the villous syncytiotrophoblasts but not in the cytotrophoblasts.The immunoreactive intensity for EGF-R decreased with the development of pregnancy.Concerning the intermediate trophoblasts in cell islands and cell columns,both proteins were more easily detected in the cells distal to the villous stroma than in the juxtastromal cells.These findings suggest that EGF-R and C-erbB-2 may play a significant role in the induction and regulation of differentiated trophoblast function |
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| Keywords: | placental trophoblast differentiation epidermal growth factor receptor C-erbB-2 Oncogene |
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