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陕西地区人群C_3的遗传多态性研究
引用本文:薛明战,牛晓洪,林田,周围,张建耕.陕西地区人群C_3的遗传多态性研究[J].西安交通大学学报(医学版),1990(1).
作者姓名:薛明战  牛晓洪  林田  周围  张建耕
作者单位:西安医科大学医学遗传学教研室 (薛明战,牛晓洪,林田),西安市中心血站 (周围),西安市中心血站(张建耕)
摘    要:用琼脂糖高压电泳继以免疫固定法对陕西地区273人补体第三组分(C_3)进行了分型.结果显示陕西地区人群中存在有两种C_3表型即SS、FS。其中SS的表型频率为98.53%,FS表型频率为1.47%,C_3S等位基因频率为0.9926,C_3F等位基因频率为0.0073。与国内其它汉族人群的分布一致,并与Hardy-weinbcng平衡相吻合。

关 键 词:C_3  遗传多态性  琼脂糖电泳免疫固定

C_3 POLYMORPHISM IN CHINESE POPULATION IN SHAANXI
Xue MingZhan,Niu Xiaohong Lin Tian.C_3 POLYMORPHISM IN CHINESE POPULATION IN SHAANXI[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1990(1).
Authors:Xue MingZhan  Niu Xiaohong Lin Tian
Institution:Medical Genetics Laboratory
Abstract:273 chinese have been studied with high voltage electrophoresis and immumofixation to survey the polymorphism of the third component of human complement in Shaanxi Provice Two C_3 phenotypes were found in this population, they are C_3SS and C_3FS The frequencies of C_3SS and C_3FS are 98.53% and 1.47% respectively. The frequency of C_3S gene is 0.9926 and C_3F gene 0.0073. These results are similar to other studies in China and this group was in Hardy-Weinberg equilibrium. Compared with Negro and Caucasian, the chinese population in Shaanxi Province has a significant difference in C_3 polymorphism.
Keywords:The third component of human combatant(C_3)  Polymorphism  Agarose gel electrophoresis  Immunofixation
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