Hierarchical Non-linear Image Registration Integrating Deformable Segmentation

A hierarchical non-linear method for image registration was presented, which integrates image segmentation and registration under a variational framework. An improved deformable model is used to simultaneously segment and register feature from multiple images. The objects in the image pair are segmented by evolving a sin- gle contour and meanwhile the parameters of affine registration transformation are found out. After that, a con- tour-constrained elastic registration is applied to register the images correctly. The experimental results indicate that the proposed approach is effective to segment and register medical images.