重症脑出血早期肠外营养的前瞻性病例对照研究

采用前瞻性病例对照的方法 ,对 38例重症脑出血患者早期肠外营养支持的作用与价值进行研究。研究组与对照组各 19例。研究组在常规治疗的基础上 ,早期使用肠外营养 (Parenteral nutrition,PN)的方法进行营养支持 ,连续使用 7d。而对照组在常规治疗的基础上 ,仅用葡萄糖、胰岛素和适量的电解质。两组同时监测血清白蛋白、血清转铁蛋白、氮平衡 ,使用 APACHE 评分系统进行病情危重程度的评估。结果发现两组的各项指标均有显著性差异。同时记录两组治疗 10日内的死亡数、并发感染数以及褥疮发生数。发现研究组的病死数、感染与褥疮发生数明显少于对照组。因此认为对重症脑出血患者进行早期肠外营养支持 ,不但能改善患者的应激性营养代谢紊乱 ,而且能提高临床疗效 ,减少并发症。

Prospective control study of early parenteral nutrition in severece rebral hemorrhage patients

Try to find out the effect and value of early parenteral nutrition (PN) in severe cerebral hemorrhage treatment.Using prospective control method, totally 38 patients were researched.Both groups had 19 subjects respectively.Continuing PN was given to case group for 7 days, and serum albumin, serum transferrin and nitrogen balance were measured.Moreover, the APACHEⅡ system was used to evaluate the patients' server status.Then recorded the numbers of death, complicated infection and bedsore happened during the period of 10 studying days.The results showed that all indexes were significantly different between the two groups.What's more, the fatality, the frequency of infection and bedsore were significantly less than control.So we think using early PN to severe cerebral hemorrhage patient is not only to improve the stressful metabolic disturbance but to raise curative effect and lower complication.