| EFFECT OF ANGELICA SINENSIS ON AFFERENT DISCHARGE OF SINGLE MUSCLE SPINDLE IN TOADS |
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| 作者姓名： | 高云芳 樊小力 |
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| 作者单位： | [2]CollegeofLifeSciences,NorthwestUniversity,Xi＇an710069,China [3]DepartmentofPhysiology,MedicalSchoolofXi＇anJiaotongUniversity,Xi＇an710061,China |
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| 基金项目： | FoundationItem:ThisprojectwassupportedbytheNationalNaturalScienceFoundationofChina(No.30300106) |
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| 摘 要： | Objective In drugs for invigorating blood circulation, to find a herb that can stimulate afferent discharge of muscle spindle. Methods A single muscle spindle was isolated from sartorial muscle of toad. Using airgap technique, afferent discharge of the muscle spindle was recorded. Effects of Angelica Sinensis, Salvia Miltiorrhiza,and Safflower on afferent discharge of the muscle spindle were observed. Results Angelica Sinensis could distinctly increase afferent discharge frequency of the muscle spindle, and this increase was dose-dependent. But Salvia Miltiorrhiza and Safflower had no this excitatory effect. Conclusion It is known that Angelica Sinensis can invigorate blood circulation, and we have found its excitatory effect on muscle spindle which makes it possible to serve people with muscle atrophy if more evidences from clinical experiments are available.
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| 关 键 词： | 当归 肌梭 气隙 废用性萎缩 |
EFFECT OF ANGELICA SINENSIS ON AFFERENT DISCHARGE OF SINGLE MUSCLE SPINDLE IN TOADS |
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| Gao Yunfang #,Fan Xiaoli #.EFFECT OF ANGELICA SINENSIS ON AFFERENT DISCHARGE OF SINGLE MUSCLE SPINDLE IN TOADS[J].Academic Journal of Xi’an Jiaotong University,2004,16(2):178-180. |
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| Authors: | Gao Yunfang # Fan Xiaoli # |
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| Institution: | 1. College of Life Sciences, Northwest University, Xi'an 710069, China.;Department of Physiology, Medical School of Xi'an Jiaotong University, Xi'an 710061, China.
2. College of Life Sciences, Northwest University, Xi'an 710069, China. |
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| Abstract: | Objective In drugs for i nvigorating blood circulation, to find a herb that can stimulate afferent discha rge of muscle spindle. Methods A single muscle spindle was isolated from sartorial mus cle of toad. Using air-gap technique, afferent discharge of the muscle spindle was recorded. Effects of Angelica Sinensis, Salvia Miltiorrhiza, and Safflower o n afferent discharge of the muscle spindle were observed. Results Angelica Sinensis could distinctly increase afferent di scharge frequency of the muscle spindle, and this increase was dose-dependent. But Salvia Miltiorrhiza and Safflower had no this excitatory effect. Conclusion It is known that Angelica Sinensis can invigorate bl ood circulation, and we have found its excitatory effect on muscle spindle which makes it possible to serve people with muscle atrophy if more evidences from cl inical experiments are available. |
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| Keywords: | Angelica Sinensis muscle spindle air-gap techni que disuse atrophy |
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