| 孕早期绒毛膜GLOI多态性研究及西安地区298例GLOI分型调查 |
| |
| 引用本文： | 阎金成,余兵,刘明俊.孕早期绒毛膜GLOI多态性研究及西安地区298例GLOI分型调查[J].西安交通大学学报(医学版),1987(3). |
| |
| 作者姓名： | 阎金成 余兵 刘明俊 |
| |
| 作者单位： | 西安医科大学法医系，西安医科大学法医系，西安医科大学法医系 |
| |
| 摘 要： | 用淀粉/琼脂糖混合凝胶平板电泳法对42例孕早期绒毛膜及其父母血液的乙二醛酶Ⅰ(Glyoxalase Ⅰ)多态性进行了研究。同时对西安地区298例献血员红细胞GLOI进行了分型调查。42例绒毛膜中38例显示出GLOI的三种普通表型:GLOI 1—1型、GLOI 2—1型、GLOI 2—2型,其酶活性与血液无明显差异,其余4例经反复电泳,未能显示出GLOI活性区带。西安地区GLOI的三个普通表型分布为:GLOI 1—1型4.36％、GLOI 2—1型27.85％、GLOI型2—2型67.79％,其基因频率为GLOI~1=0.1828,GLOI~2=0.8172,识别能力(DP)值为0.4610。
|
THE POLYMORPHISM ANALYSIS OF GLOI OF FIRST-TRIMESTER CHORIONIC VILLI AND DISTRIBUTION OF GLOI PHENOTYPES IN XI'AN POPULATION |
| |
| Yan Jingcheng,et al.THE POLYMORPHISM ANALYSIS OF GLOI OF FIRST-TRIMESTER CHORIONIC VILLI AND DISTRIBUTION OF GLOI PHENOTYPES IN XI'AN POPULATION[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1987(3). |
| |
| Authors: | Yan Jingcheng |
| |
| Institution: | Faculty of Forensic Medicine |
| |
| Abstract: | First-trimester chorionic villi, parental blood (in 42 families) and the blood from normal unrelated donors (n=298) have been analyzed by mixed starch/agrose gel electrophoresis. The three common phenotypes of GLOI have been demonstrated to exist in 38 villi samples from the 42 families. In the other 4 villi samples, the GLOI has not been found. The pheno- typo frequencies of GLOI in Xi'an were as follows: GLOI I-I 0.0436, GLOI 2-I= 0.2785, GLOI 2-2=0.6779. The gene frequencies were at GLOI~1=0.1828, GLOI~2= 0.8172. The discrimination power (DP) of GLOI was 0.461. |
| |
| Keywords: | GLOI (glyoxalase I) chorionic villi starch/agarosc gel electrophoresis |
| 本文献已被 CNKI 等数据库收录！ |
