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雌激素受体在肝海绵状血管瘤中的表达及意义
引用本文:汪根树,刘青光,潘承恩,杨威,张梅.雌激素受体在肝海绵状血管瘤中的表达及意义[J].西安交通大学学报(医学版),1999,20(3):384-385.
作者姓名:汪根树  刘青光  潘承恩  杨威  张梅
作者单位:西安医科大学第一临床医学院肝胆外科,西安,710061
摘    要:采用免疫组化S P法检测30 例肝海绵状血管瘤(Cavernous hem anjiom aofliver,CHL)组织中雌激素受体(Estrosen receptor, ER)的表达,并以CHL瘤旁正常肝组织作对照。结果ER 阳性表达于CHL 血窦内皮细胞胞浆中,阳性率为433% ;CHL瘤旁正常肝组织中未见表达( P< 0.05)。提示肝海绵状血管瘤的生长与雌激素有关。雌激素可能通过其受体作用促进CHL生长

关 键 词:海绵状血管瘤  肝肿瘤  雌激素受体

THE EXPRESSION OF ESTROGEN RECEPTOR IN CAVERNOUS HEMANGIOMA OF THE LIVER AND IT'S SIGNIFICANCE
Wang Genshu, Liu Qingguang, Pan Cheng''''en et al.THE EXPRESSION OF ESTROGEN RECEPTOR IN CAVERNOUS HEMANGIOMA OF THE LIVER AND IT'S SIGNIFICANCE[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1999,20(3):384-385.
Authors:Wang Genshu  Liu Qingguang  Pan Cheng'en
Institution:Wang Genshu, Liu Qingguang, Pan Cheng'en et al (Department of Hepatobiliary Surgery, First Affiliated Hospital)
Abstract:Objective: To detect estrogen receptor(ER) in cavernous hemangioma of the liver and discuss it's significance.Methods:Paraffin tissue sections of 30 CHL and 10 paratumor normal hepatic tissue (PTNH),ER was detected by immunohistochemical method of S P.Results:ER was present in cytoplasm of endothelial cells of the blood sinus of CHL by positive rate of 43.3% and was not found in all PTNHT.The positive rates in CHL and PTNHT were different significantly.Conclusion:The growth of CHL is relative to estrogen.Estrogen promote the growth of CHL by it's receptor ER.This study presents some clues for searching hormon therapy of CHL.
Keywords:cavernous hemangioma  liver neoplasma  estrogen receptor
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