| EFFECTS OF SALVIA MILTIORRHIZA BUNGE（SMB）ON LIPID PEROXIDATION AND PLASMA MEMBRANE FLUIDITY OF CULTU |
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| 引用本文： | 和水祥,舒昌杰,韩瑽,任瑛云,李广元.EFFECTS OF SALVIA MILTIORRHIZA BUNGE（SMB）ON LIPID PEROXIDATION AND PLASMA MEMBRANE FLUIDITY OF CULTU[J].西安交通大学学报(英文版),1995(1). |
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| 作者姓名： | 和水祥 舒昌杰 韩瑽 任瑛云 李广元 |
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| 作者单位： | Department of Infectious Diseases，First Affiliated Hospital，Xi'an Medical University，Xi'an 710061 |
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| 摘 要： | ＥＦＦＥＣＴＳＯＦＳＡＬＶＩＡＭＩＬＴＩＯＲＲＨＩＺＡＢＵＮＧＥ（ＳＭＢ）ＯＮＬＩＰＩＤＰＥＲＯＸＩＤＡＴＩＯＮＡＮＤＰＬＡＳＭＡＭＥＭＢＲＡＮＥＦＬＵＩＤＩＴＹＯＦＣＵＬＴＵＲＥＤＨＵＭＡＮＦＥＴＡＬＨＥＰＡＴＯＣＹＴＥＳＩＮＪＵＲＥＤＢＹＣＡＲＢ...
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EFFECTS OF SALVIA MILTIORRHIZA BUNGE(SMB)ON LIPID PEROXIDATION AND PLASMA MEMBRANE FLUIDITY OF CULTURED HUMAN FETAL HEPATOCYTES INJURED BY CARBON TETRACHLORIDE |
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| He Shuixiang,Shu Chaugjie,Han Cong,Ren Yingyun,Li Guangyuan.EFFECTS OF SALVIA MILTIORRHIZA BUNGE(SMB)ON LIPID PEROXIDATION AND PLASMA MEMBRANE FLUIDITY OF CULTURED HUMAN FETAL HEPATOCYTES INJURED BY CARBON TETRACHLORIDE[J].Academic Journal of Xi’an Jiaotong University,1995(1). |
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| Authors: | He Shuixiang Shu Chaugjie Han Cong Ren Yingyun Li Guangyuan |
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| Abstract: | In order to investigate the effect of salvia miltiorrhiza hunge(SMB)on the plasma membrane fluidity and the relationship between the lipid peroxidation and the Plasma membrane fluidityin cultured human fetdal hepatocytes,the plasma membrane fluidity,using 1,6-dipheny-1,3,5-hexatriene(DPH)as a fluorescence probe, malondialdehyde(MDA)production as well as alanine aminotransferase(ALT)release of human fetal hepatocytes cultured in Presence of carbon tetrachloride(CCl4)or SMB puls CCl4 were estimated. In the cultured hepatocytes injured by CCl4,significant increments of the MDA production and the ALT release,and significant decrease in the plasma membrane fluidity were observed.when the culture medium was supplied with SMB prior to the additionof CCl4,the CCl4 induced increments in MDA production and ALT release was suppressed signifi cantly and a concomitant raise of plasma membrane fluidity towards normal occurred.The resultssuggested that SMB could suppress the lipid peroxidation in bepatocytes,thereby normal membranefluidity might be retained. |
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| Keywords: | salvia miltiorrhiza bunge(SMB) human fetal hepatocyte lipid peroxidation membrane fluidity |
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