| 血清唾液酸、岩藻糖测定对癌瘤患者的检测、诊断意义 |
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| 引用本文： | 何贞观,贾锡安,曹敏.血清唾液酸、岩藻糖测定对癌瘤患者的检测、诊断意义[J].西安交通大学学报(医学版),1982(1). |
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| 作者姓名： | 何贞观 贾锡安 曹敏 |
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| 作者单位： | 西安医学院生化教研室
(何贞观，贾锡安)，西安医学院生化教研室(曹敏) |
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| 摘 要： | 本组测定了各种癌瘤患者血清中唾液酸和岩藻糖的含量,结果表明恶性肿瘤患者血清中唾液酸含量大部分增高,阳性率为72.38%,又因为良性肿瘤和其它非癌瘤病变为肝硬化、胃溃疡等的患者,其血清中唾液酸含量基本上都在正常范围,因此血清中唾液酸含量的测定有助于恶性癌瘤的诊断及鉴别诊断,至于血清中岩藻糖含量虽亦升高,但其阳性率较低,且其它疾病时亦易出现阳性,故仅能作为参考。
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The Examinal and Diagnostic Value of Measurement of Serum Sialic Acid and Fucose in Patients with Carcinoma |
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| Abstract: | The sialic acid and fucose are important imgredients of glycoprotein and glycolipid of cell membrane. It is well known that they are closelyrelated to the malignant beheviors of carcinoma cells. In the series of study we measured the contents of serum sialic acid andfucose in 150 samples of patients with variant carcinoma and 64 samples ofother noucancer patients. The results showed that most of the patients withcarcinoma had an increased content of serum sialic acid, but the patientswith other diseases, such as liver cirrhose, had not. So we came to theconclution that the measurement of serum sialic acid could be used as amethod for diagnosing carcinoma. The elevation of the content of serumfucose, however, was not as evident as serum sialic acid. |
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