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| 酒精诱导的小鼠生殖系统损伤与一氧化氮的关系 | |
| 引用本文： | 黄辰,康新勤,宋土生,司履生,倪磊,张庆华,胡晓岩,胡劲松.酒精诱导的小鼠生殖系统损伤与一氧化氮的关系[J].西安交通大学学报(医学版),2003,24(1):30-31. |
| 作者姓名： | 黄辰 康新勤 宋土生 司履生 倪磊 张庆华 胡晓岩 胡劲松 |
| 作者单位： | 1. 西安交通大学医学院生物学暨医学遗传学教研室,西安,710061;西安交通大学生命科学与技术学院肿瘤研究所,西安,710061 2. 西安交通大学医学院生物学暨医学遗传学教研室,西安,710061 3. 西安交通大学生命科学与技术学院肿瘤研究所,西安,710061 4. 陕西省旬邑县医院,旬邑,711300 |
| 摘 要： | 目的 研究酒精饲养小鼠精子死亡率和活动率与睾丸一氧化氮 (NO)形成的关系。方法 应用灌胃的方法饲养酒精组小鼠 ,并检测小鼠精子死亡率、活动率以及睾丸NO含量和NOS活性。结果 酒精饲养小鼠精子死亡率明显高于对照组 ,而活动率以及NO含量和NOS活性均低于对照组。结论 酒精诱导小鼠精子质量下降与NO浓度有关 |
| 关 键 词： | 精子 酒精 一氧化氮 |
| 文章编号： | 1671-8259(2003)01-0030-02 |
| 修稿时间： | 2002年5月27日 |
The relationship between NO and the mouse reproductive system injury induced by alcohol |
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| Abstract: | Objective To study the relationship between NO and mouse reproductive system injury induced by alcohol. Methods Alcohol was administered through gastric tube in mouse. The sperm viability and mobility were studied by means of testing the sperm quality; the concentration of NO and activity of NOS were tested. Results The viability and mobility of sperms from the mice fed by alcohol were weaker than those of the normals; NO concentration and NOS activity in the testicles were lower than the normal's. Conclusion The reduction of sperm quality of the mice fed by alcohol is related to the decline of NO concentration in the testicles. |
| Keywords: | sperm alcohol NO |
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