经宫颈活取早孕绒毛作产前诊断方法的研究

本文对155例早孕妇女进行了经宫颈获取绒毛方法的研究,并对三种不同来源与直径的抽吸管效果进行了对比。临床实验研究证实在B超指示下取材的成功率较盲吸法高,可达99%。改进后的Ⅱ型吸管将钢丝固定在吸管外,操作时不用抽管芯,比进口管操作简便,取一次检材成功率可达85%,实验结果表明,胚胎着床在子宫后壁较易取材成功。孕期7～8周时,在B超指示下取材一次成功率最高,且取到的组织量也最多。20例孕妇在活取绒毛后观察了3～7天后行人流术。近期观察无一例发生流产和胚胎宫内死亡,证明了本操作的安全性。

TRANSCERVICAL CHORIONIC VILLUS ASPIRATION FOR PRENATAL DIAGNOSIS IN EARLY PREGNANCY

The technique of transcervical chorionic villus sampling (TCVS) was studied in 155 cases for selected abortion in the first trimester of pregnancy, and 3 kinds of suction tube were compared. The ultrasonic mothod for the aspiration of chorionie villus sampling is more effective than the blind aspiration, giving a success rate of 99%. The modified suction tube with a stainless steel wire along-side as a supporter is simpler than the Portex's tube, giving a oneshot success rate of 85%. This shows that the TCVS is more satisfactory if the embryo is implanted into the posterior wall of the uterus. With the B-mode scanner, it gives the highest one-shot success rate and the amount of the obtained tissue is the greatest in the 7th and 8th weeks of gestation. Twenty cases were followed up for 3 to 7 days after the procedure before selective abortion. No complications occurred during and after the TCVS, indicating that this technique ia simple, safe and reliable.