| EFFECTS OF SALVIA MILTIORRHIZA BUNGE （SMB） ON LIPID PEROXIDATION OF CULTURED HUMAN FATAL HEPATOCYTES |
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| 引用本文： | 和水祥,舒昌杰,韩瑽,任瑛云,李广元.EFFECTS OF SALVIA MILTIORRHIZA BUNGE （SMB） ON LIPID PEROXIDATION OF CULTURED HUMAN FATAL HEPATOCYTES[J].西安交通大学学报(英文版),1994(2). |
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| 作者姓名： | 和水祥 舒昌杰 韩瑽 任瑛云 李广元 |
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| 作者单位： | He Shuixiang; Shu Changjie; Han Cong; Ren Yingyun Li Guangyuan (Department of Infectious Diseases，First Affiliated Hospital，Xi'an Medical University，Xi'an 710061) ( Research Institute of Endemic Bone Disease) |
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| 摘 要： | ＨｅＳｈｕｉｘｉａｎｇ（和水祥）；ＳｈｕＣｈａｎｇｊｉｅ（舒昌杰）；ＨａｎＣｏｎｇ（韩瑽）；ＲｅｎＹｉｎｇｙｕｎ（任瑛云）；ＬｉＧｕａｎｇｙｕａｎ（李广元）ＥＦＦＥＣＴＳＯＦＳＡＬＶＩＡＭＩＬＴＩＯＲＲＨＩＺＡＢＵＮＧＥ（ＳＭＢ）ＯＮＬＩＰＩＤＰＥＲ...
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EFFECTS OF SALVIA MILTIORRHIZA BUNGE (SMB) ON LIPID PEROXIDATION OF CULTURED HUMAN FATAL HEPATOCYTES |
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| He Shuixiang, Shu Changjie, Han Cong, Ren Yingyun Li Guangyuan.EFFECTS OF SALVIA MILTIORRHIZA BUNGE (SMB) ON LIPID PEROXIDATION OF CULTURED HUMAN FATAL HEPATOCYTES[J].Academic Journal of Xi’an Jiaotong University,1994(2). |
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| Authors: | He Shuixiang Shu Changjie Han Cong Ren Yingyun Li Guangyuan |
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| Abstract: | The role of salvia miltiorrhiza bunge (SMB) In protection of lipid peroxidation induced by CCl4 was studied in primary cultured human fetal hepatocytes. The results showed that SMB had significant effect inhibiting lipid peroxidation of the hepatocytes when exposed to CCl4 as compared with the non-protective co4trol. SMB could decrease the production of malondialdehyde (MDA) and the release of ALT, and increase the synthesis of albumin (ALB) and the activity of Se-dependent glutothione peroxidase (Se-GSH-Px). These results suggest that the suppression of lipid peroxidation may be largely due to the increased activity of Se-GSH-Px. |
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| Keywords: | salvia miltiorrhiza bunge (SMB) CCl4 lipid peroxidation cultured cells human liver antioxidants |
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