妇科多原发性癌瘤52例报告

本文报告1966年1月～1987年12月我院放射治疗妇科肿瘤12 395例,其中多原发性癌瘤52例,发生率为0.42%。近两年来发生率为1.77%,有逐年升高的趋势。52例多原发性癌瘤中51例为双原发性癌瘤,三原发性癌瘤1例,以宫颈癌合并其他癌瘤为最多,占86.54%。发生在生殖系统的33例(63.46%),发生在非生殖系统的19例(36.54%)。发病年龄与单发性癌瘤相似。妇科双原发性癌瘤1年内发生者占36.29%,5年内发生者占62.75%,平均间隔时间为5.01年,较一般双原发性癌瘤平均间隔时间6.2年为短。52例多原发性癌瘤的治疗以放射治疗为主,其1、3、5年生存率分别为77.50%、36.36%和26.32%。

A REPORT OF 52 CASES MULTIPLE PRIMARY MALIG-NANT TUMORS (MPMT) IN FEMALE GENITAL ORGANS

52 out of 12395 cases with tumors of the female gernital organs treated in our hospital from Jan. 1966 to Dec, 1987 were MPMT. The incidence was 0.42%, but it was 1.77% in recent two years of them. 51 patients were two primaries, 1 was three primaries. The cervical carcinoma with another primaries are most common(86.54%). 33 cases (63. 46%) of the MPMT occured in genital organs and 19 (36.54%) coceured in non-genital organs. The age of the MPMT was similar to the single primary tumors, 36.29% of the patients developed a secondary primary tumor within 1 year, and 62.75% within 5 years, which is shorter than the general MPMT of which the mean intenval was 6.2 years. 52 patients were trcated with radiotherapy, the survival rate in 1, 3 and 5 years was 77.50%, 33.36% and 26.32% respectively.