血清SCC与宫颈癌生物学行为的相关性及临床意义 |
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引用本文: | 刘晓玲,车少敏,王文,姜缨,郑伟.血清SCC与宫颈癌生物学行为的相关性及临床意义[J].西安交通大学学报(医学版),2004,25(6):576-577. |
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作者姓名: | 刘晓玲 车少敏 王文 姜缨 郑伟 |
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作者单位: | 西安交通大学第一医院放疗科,陕西西安,710061 |
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摘 要: | 目的 探讨宫颈癌患者放射治疗前后血清鳞状上皮细胞癌抗原 (SCC Ag)与其生物学行为的相关性及临床意义。方法 采用全自动快速粒子酶免疫分析系统 ,检测 5 0 0例宫颈癌患者治疗前后SCC Ag值 ,分析SCC Ag检测值与宫颈癌临床病理特征之间的关系。结果 宫颈癌患者治疗前血清SCC Ag水平与肿瘤组织学类型、临床分期呈正相关 (P <0 .0 0 5 ) ,与肿瘤组织分化程度无关 (P >0 .0 5 ) ;且治疗前的水平高于治疗后 (P <0 .0 0 5 )。结论 治疗前后血清SCC Ag值对估计宫颈癌的生物学行为和预后有重要的临床参考价值
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关 键 词: | 宫颈肿瘤 鳞癌抗原 临床病理特征 |
文章编号: | 1671-8259(2004)06-0576-02 |
修稿时间: | 2004年3月15日 |
The clinical significance and the relationship between the serum squamous cell carcinoma antigen level and the biological characteristics of cervical carcinoma |
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Abstract: | Objective To investigate the clinical significa nc e and the relationship between the serum squamous cell carcinoma antigen (SCC-A g) levels and the biological characteristics in patients with cervical carcinoma . Methods The pre-post-treatment sera from 500 patients w ith cervical carcinoma from 1998 to 2002 were analyzed for the SCC-Ag levels by IMX; and the correlation between the SCC-Ag level and the clinicopathologic ch aracteristics were also detected. Results Significant corre lation was found between the pre-treatment SCC-Ag level and pathologic classif ication, and clinical stage (P<0.005); no relation was found between the pre -treatment SCC-Ag level and the pathologic grade (P>0.05); The pre-treatm ent SCC-Ag level is significantly higher than that of post-treatment (P< 0.005).Conclusion Pre-post-treatment SCC-Ag levels plays an imp ortant role in evaluating the biological characteristics and prognosis in patien ts with cervical cancer. |
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Keywords: | cervical neoplasm squamous cell carcinoma antige n(SCC-Ag) clinical pathologic characteristics |
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