| DIFFERENTIAL DIAGNOSIS IN THE INTRACRANIAL DISEASES： PROTON MAGNETIC RESONANCE SPECTROSCOPY STUDY |
| |
| 引用本文： | 鱼博浪,郭世萍,张明,孙亲利.DIFFERENTIAL DIAGNOSIS IN THE INTRACRANIAL DISEASES： PROTON MAGNETIC RESONANCE SPECTROSCOPY STUDY[J].西安交通大学学报(英文版),2004,16(2):136-139. |
| |
| 作者姓名： | 鱼博浪 郭世萍 张明 孙亲利 |
| |
| 作者单位： | Clinical Imaging Center，First Hospital of Xi'an Jiaotong University，X i'an 710061，China，Clinical Imaging Center，First Hospital of Xi'an Jiaotong University，X i'an 710061，China，Clinical Imaging Center，First Hospital of Xi'an Jiaotong University，X i'an 710061，China，Clinical Imaging Center，First Hospital of Xi'an Jiaotong University，X i'an 710061，China |
| |
| 基金项目： | ThisworkwassupportedbytheNaturalScienceFoundationofShaanxiProvince,China(No.2001SM84). |
| |
| 摘 要： | Protonmagneticresonancespectroscopy (1H MRS)isanewtechniqueoffunctionalimaginginbrainandprovidesauniquenoninvasivetoolforex aminingmetabolisminvivonow .Inrecentyear ,therearesomereportsaboutprotonMRSingrowthofbrainandhypoxia ischemicencephalopathy(HIE) 1- 4] ,butfewarticlesaboutclinicalapplica tionofprotonMRSindiagnosistumoursandtheirdifferentiationfromnon neoplasticlesions .WestudiedMRSin 38braintumorsand 14brainnon neoplasticlesions.Herewereporttheresults .MATERIALSANDMethods1 …
|
| 关 键 词： | ^1H-MRS l-asp NAA |
DIFFERENTIAL DIAGNOSIS IN THE INTRACRANIAL DISEASES:PROTON MAGNETIC RESONANCE SPECTROSCOPY STUDY |
| |
| Yu Bolang,Guo Shiping,Zhang Ming,Sun Qinli Clinical Imaging Center,First Hospital of Xi'an Jiaotong University,X i'an ,China..DIFFERENTIAL DIAGNOSIS IN THE INTRACRANIAL DISEASES:PROTON MAGNETIC RESONANCE SPECTROSCOPY STUDY[J].Academic Journal of Xi’an Jiaotong University,2004,16(2):136-139. |
| |
| Authors: | Yu Bolang Guo Shiping Zhang Ming Sun Qinli Clinical Imaging Center First Hospital of Xi'an Jiaotong University X i'an China |
| |
| Institution: | Clinical Imaging Center, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China. |
| |
| Abstract: | Objective To investigate the value of proton magnetic resonance spectroscopy (1H-MRS) on diagnosis and differential diagnosis of the intracranial diseases by the MRS results of 52 patients. Methods 12 patients with benign glioma, 16 patients with malignant glioma, 10 patients with meningioma, 8 patients with virus encephalitis, and 6 patients with cerebral infarction underwent MRS in the lesion region. We measured the area within the spectra of N-acetyl-aspartate (NAA), creatine/phosphocreatine (Cr), choline compounds (Cho), and lactate (Lac). Results The spectra of meningiomas were characterized by absence of NAA. The spectra of gliomas were characterized by the decrease of NAA and Cr, but the increase of Cho. The ratio of Cho to Cr was 2.25±1.21 in benign gliomas, while the ratio of Cho to Cr was 4.65±2.21 in malignant gliomas. The spectra of virus encephalitis appeared the decrease of NAA and the normality of Cr, with the 1.25±0.21 ratio of Cho/Cr. The apparent Lac wave could be seen in all cerebral infarctions. Conclusion The value of 1H-MRS plays a significant role in the diagnosis and differential diagnosis of gliomas, meningiomas, virus encephalitis, and cerebral infarctions. |
| |
| Keywords: | H-MRS brain tumor differential diagnosi s |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
