77例乳癌针吸细胞学检查与病理组织学检查的对照分析

<正> 应用针吸细胞学检查在临床上诊断乳房包块已获得了普遍的重视和肯定。目前已逐渐广泛应用于乳腺癌诊断。我们在临床实际工作中,应甩此方法已近十年,为了提高细胞学诊断水平,现就77例乳癌针吸细胞学检查和切除标本组织学检查进行对照分析如下。资料与方法 1973年1月—1982年12月我科对乳腺肿块应用针吸细胞学检查共125例,其中20例临床和细胞学不怀疑恶性病变;5例乳腺增生病,细胞学检查显示轻度上皮增生;23例细胞学诊

Comparative Analysis of Nspiration Cytologic and Pathohistologic Studies of 77 Cases of Breast Cancer

In the present study 77 cases of breast cancer were selected to compare the results of cytologic and pathohistologic studies of patients examined both by aspiration cytology before operation and deliberate biopsy after the specimen was removed. In this series, 52 cases (67.5％) were clinically diagnosed as breast cancer. The positive rate of aspiration cytologic diagnosis was 85.7％, and the false negative rate was 14.3％. The accuracy of diagnosis was dependent on (1) the size of the tumor, (2) the histologic type, (3) the expirience of the pathologist who observed specimens, and (4) the technical competence for taking specimens by needle aspiration. In all cases which were diagnosed as or suspected to be breast cancer but had a negative or undefined result on cytologic examination such examination or biopsy should be carried out again. There were no complications, implants or tumor cells spread around the needle hole after needle aspiration in this series, indicating that the cytologic method is simple, safe and reliable. Although different histologic types of breast cancer had different cytologic characteristics, its histologic diagnosis was in accordance with the cytologic one in 44.2％ of patients only. Because of the mixed type of breast cancer and the restriction of needle aspiration as well as the various differentiation of tumors, we agree that at present it is not adequate to classify breast cancer according to its cytologic results.