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THE EFFECT OF INTERNAL AND EXTERNAL CAROTID ARTERIAL INFUSION CHEMOTHERAPY ON 41 ADVANCED HEAD AND N
引用本文:李树业,徐荣,谢文堃,门伯媛.THE EFFECT OF INTERNAL AND EXTERNAL CAROTID ARTERIAL INFUSION CHEMOTHERAPY ON 41 ADVANCED HEAD AND N[J].西安交通大学学报(英文版),1995(2).
作者姓名:李树业  徐荣  谢文堃  门伯媛
作者单位:Shaanxi Provincial Cancer Institute,Xi'an 710061
摘    要:THEEFFECTOFINTERNALANDEXTERNALCAROTIDARTERIALINFUSIONCHEMOTHERAPYON41ADVANCEDHEADANDNECKCANCER PATIENTSLiShuye;XuRong;XieWenk...


THE EFFECT OF INTERNAL AND EXTERNAL CAROTID ARTERIAL INFUSION CHEMOTHERAPY ON 41 ADVANCED HEAD AND NECK CANCER PATIENTS
Li Shuye,Xu Rong,Xie Wenkun, Men Boyuan,.THE EFFECT OF INTERNAL AND EXTERNAL CAROTID ARTERIAL INFUSION CHEMOTHERAPY ON 41 ADVANCED HEAD AND NECK CANCER PATIENTS[J].Academic Journal of Xi’an Jiaotong University,1995(2).
Authors:Li Shuye  Xu Rong  Xie Wenkun  Men Boyuan  
Abstract:advanced head and neck cancer patients who couldn't be cured by surgery were treated by internal and external carotid arterial infusion via thyroid superior artery,temporal superficial artery or carotid artery with Fluorocuracil (SFu),Pingyangmycini(PYM),Carmustine (BCNU),Nidran Ampooles (ACNU) and Methotrexate (MTX).The results suggested that, the combining application of different drugs acting at different phases in cell replication cycle might play a coordinated role,before chemotherapy the application of hyperosmotic mannitol and corticoid might open the blood brain barrier temporarily and increase the drug uptake by brain tissue.As compared with ultra-selective internal carotic arterial chemotherapy,the treatment intubating into internal carotid artery via thyroid superior artery and leaving the tube in the artery is much easier, safer and cheaper and has fewer complications,so it is readily accepted by patients.
Keywords:head and neck cancer  arterial infusion  chemotherapy
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