| MgSO_4对实验性心律失常的作用 |
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| 引用本文： | 吴捷,李孝光,臧伟进.MgSO_4对实验性心律失常的作用[J].西安交通大学学报(医学版),1989(1). |
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| 作者姓名： | 吴捷 李孝光 臧伟进 |
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| 作者单位： | 西安医科大学医学电子工程研究室
(吴捷，李孝光)，西安医科大学医学电子工程研究室(臧伟进) |
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| 基金项目： | 国家自然科学基金资助的课题,编号414 |
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| 摘 要： | 本实验研究了MgSo_4对实验性心律失常的作用。结果表明MgSO_4:可对抗哇巴因诱发豚鼠心律失常;可减少氯仿对小鼠的致颤率;能减少乌头碱诱发大鼠心律失常的时间;可对抗氯仿—肾上腺素诱发家兔心律失常;能使BaCl_2所致大鼠心律失常复转为窦性心律。MgSO_4对抗心律失常作用与传统药物苯妥英纳相似。
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THE EFFECTS OF MAGNESIUM ON EXPERIMENTAL ARRHYTHMIA |
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| Wu Jie,et al.THE EFFECTS OF MAGNESIUM ON EXPERIMENTAL ARRHYTHMIA[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1989(1). |
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| Authors: | Wu Jie |
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| Institution: | Research Laboratory of Medical Electronic Engineering |
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| Abstract: | Magnesium is one of the important io-ns in humau body.MgSO_4 150mg/kg sho-wed an action of antiventricular fibrillationcausel by inspiring chloroform in guineapigs.In rats anaesthetized by Ⅳ chloralhydrate 300mg/kg,arrhythmin induced by Ⅳ BaCl_2 4 mg/kg was recovered to anor-mal sinus rhythm cansed by Ⅳ MgSO_4100 mg/kg.Ⅳ MgSO_4 50 mg/kg wasfound to protect rabbits against arrhythmiainduced by chloroform-adrena line.In theanaesthetized guinea pigs,Ⅳ MgSO_4 100mg/kg raised the amount of ouabain indu-cing first arrhythmias,ventricular fibrilla-tion and heart arrest.In the anaesthetizedrats.Ⅳ MgSO_4 100 mg/kg raised the am-ount of aconitine inducing arrhythmias.Theresults showed that MgSO_4 has a good ef-fect on antagonise arrhythmias. |
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| Keywords: | magnesium arrhychmia ouabain aconitine chloroform adrena |
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