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| 甲亢伴甲状腺炎与桥本氏甲亢的免疫病理研究 | |
| 引用本文： | 苏敏,牛恕淼. 甲亢伴甲状腺炎与桥本氏甲亢的免疫病理研究[J]. 西安交通大学学报(医学版), 1990, 0(3) |
| 作者姓名： | 苏敏 牛恕淼 |
| 作者单位： | 西安医科大学病理解剖学教研室(苏敏)，西安医科大学病理解剖学教研室(牛恕淼) |
| 摘 要： | 本文对13例甲亢伴甲状腺炎和9例桥本氏甲亢进行了病理形态及免疫组化研究。发现桥本氏甲亢患者甲状腺浸润细胞的总数较甲亢伴甲状腺炎明显增多,且炎性破坏程度也显著加剧。单个核细胞亚群免疫组化研究结果揭示:甲状腺浸润细胞以T淋巴细胞为主,甲亢伴甲状腺炎与桥本氏甲亢二者甲状腺漫润细胞各亚群百分比含量大致相近,仅桥本氏甲亢甲状腺浸润的活化T淋巴细胞百分比略高。提示二者可能存在类似的免疫病理机制。 |
| 关 键 词： | 甲亢伴甲状腺炎 桥本氏甲亢 单个核细胞亚群 免疫组化研究 |
IMMUNOPATHOLOGIC STUDY IN THYROTOXICOSIS WITH THYROIDITIS AND HASHIMOTOXICOSIS |
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| Su Min Niu Shumiao. IMMUNOPATHOLOGIC STUDY IN THYROTOXICOSIS WITH THYROIDITIS AND HASHIMOTOXICOSIS[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1990, 0(3) | |
| Authors: | Su Min Niu Shumiao |
| Affiliation: | Department of Pathology |
| Abstract: | A morphologic and immunohistochemical studies were performed on the thyroid tissue of 13 thyrotoxicosis with thyroiditis(TTOT) and 9 hashimotoxocosis(HSHT). We found that the inflmmatory injure in HSHT was stronger than that in TTOT, and also, there were (?)ore infiltrating cells and activated T cells in HSHT (?) that in TTOT. Nevertheless, in both HSHT and TTOT, most of the infiltrating mononclear cells were T lymphocytes, and the proportion of T cell subsets, B lymphocytes and macrophages were almost the same, suggesting there might. be similar immunopathogencsis in these two diseases. |
| Keywords: | thyrotoxicosis with thyroiditis hashimotoxicosis mononuclear cell subsets immunohistochemical |
| 本文献已被 CNKI 等数据库收录！ | |