| 大剂量甲孕酮治疗晚期乳腺癌23例分析 |
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| 引用本文： | 张珍华,李蓉,潘曼丽,刘春杰,李恩孝.大剂量甲孕酮治疗晚期乳腺癌23例分析[J].西安交通大学学报(医学版),1996(1). |
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| 作者姓名： | 张珍华 李蓉 潘曼丽 刘春杰 李恩孝 |
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| 作者单位： | 西安第一附属医院肿瘤科 |
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| 摘 要： | 给２３例晚期乳腺癌患者单用大剂量甲孕酮：５００ｍｇ／次，前３ｄ２次／ｄ，以后为１次／ｄ，持续３０ｄ为一疗程。自觉症状改善者为８６％，近期客观有效率为６０．８％，以骨转移效果为佳。既往用三苯氧胺以及氨格鲁米特无效者再用大剂量甲孕酮仍分别有４／７及２／３的患者有效。副作用轻微，偶见阴道出血、向心性肥胖。
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| 关 键 词： | 甲孕酮 乳腺癌 内分泌治疗 |
TREATMENT FOR ADVANCED BREAST CANCER WITH HIGH DOSE MEDROXYPROGESTERONE |
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| Zhang Zhenhua, Li Rong, Pan Manli,et al.TREATMENT FOR ADVANCED BREAST CANCER WITH HIGH DOSE MEDROXYPROGESTERONE[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1996(1). |
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| Authors: | Zhang Zhenhua Li Rong Pan Manli |
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| Abstract: | High dose medroxyprogesterone (HD-MPA),500 mg a time,the first three days twiceaday,then one time a day,thirty days being a cycle of treatment.20(86%)patients felt better,recent objective efficiency was 60.8%,bone metastasis re spondedbetter. 4/7 and2/3 patientskmng in prior Tanosifenand and Aminoglutethmide therapy still responded to HD-MPA. The side effects were vagina bleeding and fatting. |
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| Keywords: | medroxyprogesterone breast cancer endocrine therapy |
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