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肌梭传入对脊髓背角会聚神经元伤害性诱发反应的影响
引用本文:樊小力,魏继业,朱衡,俞泳蓓. 肌梭传入对脊髓背角会聚神经元伤害性诱发反应的影响[J]. 西安交通大学学报(医学版), 1992, 0(4)
作者姓名:樊小力  魏继业  朱衡  俞泳蓓
作者单位:西安医科大学生理学教研室,西安医科大学生理学教研室,西安医科大学生理学教研室,西安医科大学生理学教研室 西安 710061,西安 710061,西安 710061,西安 710061
摘    要:本文用细胞外微电极记录技术,以大鼠脊髓背角WDR神经元伤害性诱发反应为痛反应的指标,观察了牵拉腓肠肌诱发的肌梭传入活动对脊髓背角WDR神经元伤害性反应的影响。结果如下:在观察到的80个WDR神经元中,有51个单位的晚串放电被牵拉诱发的肌梭传入活动所抑制,16个单位无反应,13个单位表现为兴奋。对有抑制作用的51个单位的进一步观察发现,瞬时牵拉的抑制作用强于持续牵拉,双侧牵拉的抑制作用强于单侧牵拉。提示肌梭作为肌肉丰厚处穴位的主要针感感受器,其传入活动具有镇痛作用。

关 键 词:脊髓背角  会聚神经元  肌梭传入  镇痛作用

THE EFFECTS OF SPINDLE AFFERENTS ON NOCICEPTIVE RESPONSES OF CONVERGENT NEURONS IN SPINAL DORSALHORN OF RATS
Fan Xiaoli,Wei Jiye,Zhu Heng,et al. THE EFFECTS OF SPINDLE AFFERENTS ON NOCICEPTIVE RESPONSES OF CONVERGENT NEURONS IN SPINAL DORSALHORN OF RATS[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1992, 0(4)
Authors:Fan Xiaoli  Wei Jiye  Zhu Heng  et al
Affiliation:Department of Physiology
Abstract:The effects of spindle afferents activated by stretching gastrocnemius on the nociceptive responses of WDR neurons were recorded extracellularly with microelectrode and observed in paralyzed rats. The results indicated that in 51/80, the spindle afferent activity activated by stretching can inhibit nociceptive responses of neurons. 16 out of 80 neurons no effects can be observed, in 13/80 the effects of spindle afferent activity can excite the nociceptive responses of WDR neurons. Among 51 units, which have inhibitory effects induced by stretching muscle, the inhibitory effects induced by instance and bilateral stretching are stronger than that induced by continuous and unilateral stretching. These results suggested that spindle afferent activity is possesaed of analgesic effects.
Keywords:dorsal horn  convergent neurons  spindle afferent  analgesic effects
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