| 食管鳞癌组织中脾酪氨酸激酶及p53基因的表达及临床病理意义 |
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| 引用本文： | 刘泓基,臧真真,侯冰宗,侯巧燕,陆竞艳. 食管鳞癌组织中脾酪氨酸激酶及p53基因的表达及临床病理意义[J]. 西安交通大学学报(医学版), 2011, 32(1): 107-110,127 |
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| 作者姓名： | 刘泓基 臧真真 侯冰宗 侯巧燕 陆竞艳 |
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| 作者单位： | 桂林医学院附属医院消化内科,广西桂林,541001 |
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| 摘 要： | 目的 研究食管鳞状上皮细胞癌(简称食管鳞癌)组织中脾酪氨酸激酶(Syk)及p53基因的表达及二者的关系,并探讨其与食管鳞癌发生及发展的相关性.方法 用快捷免疫组化法及RT-PCR法检测食管鳞癌组织及其对应癌旁组织中Syk蛋白及mRNA的表达,同时检测p53蛋白及mRNA的表达,分析食管鳞癌中上述2个基因表达变化的相关性...
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| 关 键 词： | 食管鳞癌 免疫组织化学 RT-PCR 抑癌基因 脾酪氨酸激酶 p53 |
Expressions of Syk and p53 gene in human esophageal squamous cell carcinoma and their clinicopathological significance |
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| LIU Hong-ji,ZANG Zhen-zhen,HOU Bing-zong,HOU Qiao-yan,LU Jing-yan. Expressions of Syk and p53 gene in human esophageal squamous cell carcinoma and their clinicopathological significance[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 2011, 32(1): 107-110,127 |
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| Authors: | LIU Hong-ji ZANG Zhen-zhen HOU Bing-zong HOU Qiao-yan LU Jing-yan |
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| Affiliation: | LIU Hong-ji,ZANG Zhen-zhen,HOU Bing-zong,HOU Qiao-yan,LU Jing-yan(Department of Gastroenterology,the Affiliated Hospital ofGuilin Medical College,Guilin 541001,China) |
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| Abstract: | Objective To investigate the expressions of Syk and p53 gene in human esophageal squamous cell carcinoma and matched-adjacent tissues,and then explore their correlation with the genesis and progression of esophageal squamous cell carcinoma.Methods The expressions of Syk and p53 protein and mRNA in tumor specimens and adjacent non-tumor specimens of esophageal squamous cell carcinoma were assayed by rapid immunohistochemistry and RT-PCR method,and their correlations with patients' clinical biological behavio... |
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| Keywords: | RT-PCR p53 |
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