| ROLE OF PERIPHERAL LYMPHOCYTES SIALYL LEWIS（X） （CD15s） ANTIGEN BEFORE AND AFTER KIDNEY TRANSPLANTATION |
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| 引用本文： | 潘晓鸣,王勇,薛武军,田普训.ROLE OF PERIPHERAL LYMPHOCYTES SIALYL LEWIS（X） （CD15s） ANTIGEN BEFORE AND AFTER KIDNEY TRANSPLANTATION[J].西安交通大学学报(英文版),2006,18(2):187-190. |
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| 作者姓名： | 潘晓鸣 王勇 薛武军 田普训 |
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| 作者单位： | Department of Kidney Transplantation, the First Affiliated Hospital of Medical School, Xi＇an Jiaotong University, Xi＇an 710061, China |
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| 基金项目： | 西安交通大学校科研和教改项目 |
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| 摘 要： | Objective To investigate the role of peripheral lymphocytes Sialyl Lewis（x） （CD15s） antigen before and after kidney transplantation. Methods Flow cytometry technique was applied to examine the expression of peripheral lymphoid cell surface CD15s antigen after renal transplantation, and to evaluate various therapeutic regimen. Results The statistic analysis results of peripheral lymphoid cell surface CD15s antigen expression level showed that there was significant difference among the patients with acute rejection, long-term dialysis and with normal renal function post-transplant; significant difference of CD15s expression level between group of rejection and infection; no significant difference of CD15s expression among the different groups treated by various therapeutic regimens. Conclusion The different therapeutic regimen has no influence to CD15s expression; Detection of peripheral lymphoid cell surface CD15s antigen expression periodically, intelligently make convenience to understand suitable status of immunosuppression.
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| 关 键 词： | 肾抑制 CD15s 淋巴细胞 肾脏手术 |
| 文章编号： | 1671-8267（2006）02-0187-04 |
ROLE OF PERIPHERAL LYMPHOCYTES SIALYL LEWIS(X) (CD15s)ANTIGEN BEFORE AND AFTER KIDNEY TRANSPLANTATION |
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| Pan Xiaoming,Wang Yong,Xue Wujun,Tian Puxun.ROLE OF PERIPHERAL LYMPHOCYTES SIALYL LEWIS(X) (CD15s)ANTIGEN BEFORE AND AFTER KIDNEY TRANSPLANTATION[J].Academic Journal of Xi’an Jiaotong University,2006,18(2):187-190. |
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| Authors: | Pan Xiaoming Wang Yong Xue Wujun Tian Puxun |
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| Abstract: | Objective To investigate the role of peripheral lymphocytes Sialyl Lewis(x) (CD15s) antigen before and after kidney transplantation. Methods Flow cytometry technique was applied to examine the expression of peripheral lymphoid cell surface CD15s antigen after renal transplantation, and to evaluate various therapeutic regimen. Results The statistic analysis results of peripheral lymphoid cell surface CD15s antigen expression level showed that there was significant difference among the patients with acute rejection, long-term dialysis and with normal renal function post-transplant; significant difference of CD15s expression level between group of rejection and infection; no significant difference of CD15s expression among the different groups treated by various therapeutic regimens. Conclusion The different therapeutic regimen has no influence to CD15s expression; Detection of peripheral lymphoid cell surface CD15s antigen expression periodically, intelligently make convenience to understand suitable status of immunosuppression. |
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| Keywords: | renal transplantation CD15s immunosuppression |
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