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ALTERATIONS IN THE PROTEIN SYNTHESIS AND CONTENTS OF RIBOSOME AND POLYSOME IN LIVEROF SELENIUM-DEFICIENT RATS
引用本文:毕红,李同良,贾锡安,赵君庸.ALTERATIONS IN THE PROTEIN SYNTHESIS AND CONTENTS OF RIBOSOME AND POLYSOME IN LIVEROF SELENIUM-DEFICIENT RATS[J].西安交通大学学报(英文版),1996(1).
作者姓名:毕红  李同良  贾锡安  赵君庸
作者单位:Department of Biochemistry,Xi'an medical University,Xi'an 710061
摘    要:ALTERATIONSINTHEPROTEINSYNTHESISANDCONTENTSOFRIBOSOMEANDPOLYSOMEINLIVEROFSELENIUM-DEFICIENTRATS(毕红),(李同良)(贾锡安),(赵君庸)BiHong;Li...


ALTERATIONS IN THE PROTEIN SYNTHESIS AND CONTENTS OF RIBOSOME AND POLYSOME IN LIVEROF SELENIUM-DEFICIENT RATS
Bi Hong,Li Tongliang,Jia Xi'an,Zhao Junyong,.ALTERATIONS IN THE PROTEIN SYNTHESIS AND CONTENTS OF RIBOSOME AND POLYSOME IN LIVEROF SELENIUM-DEFICIENT RATS[J].Academic Journal of Xi’an Jiaotong University,1996(1).
Authors:Bi Hong  Li Tongliang  Jia Xi'an  Zhao Junyong  
Abstract:In the present experiments the changes in levels of ribosome,polysome and 3H-leucine incorporation rate in liver post-mitochondrial supernatant (PM-supernatant) were investigated in Sedericient and Se-supplented rats.The results demonstrated that the amounts of ribosome and polysome as well as the ratio of polysome to ribosome in liver PM-supernatant from the Se-deficient rats were all remarkahly decreased.In the meantime,the rate of protein synthesis expressed as radioactivity or 3H-leucine incorporated into protein in the PM-supernatant system also decreased significantly.The results suggest that the decreases of ribosomes and proportion of ribosomal aggregates in PM-supernatant may be responsible for the decrease of the protein synthesis activity in liver of the Se-deficient animals.
Keywords:selenium  ribosomes  polysomes  protein synthesis  rat liver
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