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大鼠移植性肝癌MRI信号特征与定量分析
引用本文:张卓立,王泽忠,郭佑民,刘继汉.大鼠移植性肝癌MRI信号特征与定量分析[J].西安交通大学学报(医学版),1999(1).
作者姓名:张卓立  王泽忠  郭佑民  刘继汉
作者单位:第一临床医学院影像中心!西安710061
摘    要:通过对Walker256移植性肝癌的动物模型的MRI图像信号以及T1值、T2值的测定分析,提出了在0.35T磁场强度下大鼠移植性肝癌MRI信号定量分析的模式和意义。提出:(1)大鼠移植瘤的T1值与正常肝组织T1值有较大重叠,诊断意义不大;(2)移植瘤T2值与正常厅组织T2值无重叠有诊断意义;(3)移植瘤T2WI-SIR值亦具有诊断意义。建议各种不同磁场强度的机器可建立自己的定量分析标准。

关 键 词:动物模型  磁共振成像  肝肿瘤

THE ANALYSIS OF CHARACTERISTICS AND QUANTITY OF MRI SIGNAL IN RATS WITH WALKER-256 PLANTED LIVER CANCER
Zhang Zhuoli, Wang Zezhong, Guo Youmin et al.THE ANALYSIS OF CHARACTERISTICS AND QUANTITY OF MRI SIGNAL IN RATS WITH WALKER-256 PLANTED LIVER CANCER[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1999(1).
Authors:Zhang Zhuoli  Wang Zezhong  Guo Youmin
Abstract:60 models of walker-256 rat plantedliver cancer were studied. The signals of MR images, T1 value and T2 value were measured andanalysed. The author brought up the formula andsignificance of quantitative analysis of planted livercancer MRI signal in 0.35 T magnetic field including① There was overlapping of T1 value between theplanted liver cancer and healthy liver tissues. T1value wasn't important for diagnosisl;② There wasnot overlapping of T2 value(下转第114页)(上接第73页)between the planted liver cancer andhealthy liver tissues. T2 value could improve thedetection of liver cancerl ③ T2 WI-SIR value wasalso significant in diagnosis. The author suggeststhat the machines in different magnetic field shouldset up their own diagnosis index of quantitative analysis of MRI signal.
Keywords:animal model  magnetic resonance imaging  liver neoplasm
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