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颅脑损伤急性期血浆凝血因子水平的变化
引用本文:高李贵,刘重霄,王卉芳,师蔚,朱建宏. 颅脑损伤急性期血浆凝血因子水平的变化[J]. 西安交通大学学报(医学版), 2003, 24(5): 505-506,509
作者姓名:高李贵  刘重霄  王卉芳  师蔚  朱建宏
作者单位:1. 西安交通大学第二医院神经外科,陕西西安,710004
2. 西安市第四人民医院病理科,陕西西安,710004
3. 西安交通大学第二医院检验科,陕西西安,710004
摘    要:目的 了解急性闭合性颅脑损伤后早期血浆凝血因子水平的变化和规律。方法对 10 6例急性闭合性颅脑损伤患者血浆凝血因子Ⅱ、Ⅴ、Ⅹ、Ⅻ进行检测。结果 ①GCS≤ 7的患者血浆所有上述凝血因子水平均异常 ,GCS >7的患者血浆凝血因子水平仅部分异常 ;②上述血浆凝血因子水平延长与颅脑损伤程度相关 ;③上述血浆凝血因子水平均异常者死亡率较高。结论 血浆凝血因子尤其是Ⅱ、Ⅴ、Ⅹ因子水平与颅脑损伤的严重程度相关 ,可为判断急性闭合性颅脑损伤患者的预后提供线索

关 键 词:颅脑损伤  凝血因子  预后
文章编号:1671-8259(2003)05-0505-02

Study on the level of blood coagulation factors in acute phase of craniocerebral injury
Gao Ligui,Liu Chongxiao,Wang Huifang,Shi Wei,Zhu Jianhong. Study on the level of blood coagulation factors in acute phase of craniocerebral injury[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 2003, 24(5): 505-506,509
Authors:Gao Ligui  Liu Chongxiao  Wang Huifang  Shi Wei  Zhu Jianhong
Abstract:Objective To investigate the changes of blood coagulation factors during acute phase of craniocerebral injuries. Methods The blood coagulation factors Ⅱ, Ⅴ, Ⅹ and Ⅻ of 106 samples were detected. Results ① There were 36 patients whose blood coagulation factors were all abnormal and whose GCS were no more than 7; ② The more the severity of head injury, the lower the level of blood coagulation factors; ③ The mortality of patients with abnormal level of blood coagulation factors Ⅱ, Ⅴ, Ⅹ and Ⅻ was higher. Conclusion It is suggested that the level of blood coagulation factors especially factors Ⅱ, Ⅴ and Ⅹ is related to the severity of head injury, and the level of the blood coagulation factors could be an index to judge the prognosis of patients suffered by craniocerebral injury.
Keywords:craniocerebral injury  blood coagulation factors  prognosis
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