| STUDY ON DETERMINATION AND APPLICATION OF THE SPECIFIC ANTIBODIES TO CYTOMEGALOVIRUS IN BONE MARROW TRANSPLANTATION |
| |
| 作者姓名： | 张梅 刘陕西 王宝燕 蔡瑞波 刘心 郭桂丽 董青 邵文斌 韩云峰 |
| |
| 作者单位： | Department of Hematology，First Affiliated Hospital，Xi'an Medical University. Xi'an710061 |
| |
| 摘 要： | Cytomegalovirus(CMV)interstitialpneumonitis(lP)isoneofthemostseriouscomplicationsafterbonemarrowtransplantation(BMT).TheincidenceofCMV--lPisusually50%andthemortalityisalmost85%--100%".'>.AstherearenoeffectiveandspecifictherapeuticmeasuresforCMV-lP,ithasbecomethefirstimportantreasonforfailureofBMT.WaysofCMVinfectionaremainlybytrnasfusion,'organtransplantation,closecontactandverticaltransmission.PatientswithBMTareusuallysusceptibletoCMV.Thesepatientshavetoreceivetotalbodyirradiation(…
|
STUDY ON DETERMINATION AND APPLICATION OF THE SPECIFIC ANTIBODIES TO CYTOMEGALOVIRUS IN BONE MARROW TRANSPLANTATION |
| |
| Zhang Met,Liu Shaanxi, Wang Baoyan, Cat Ruibo,Liu Xin,Guo Guilt, Dong Qing, Skao Wenbln, HanYunfeng.STUDY ON DETERMINATION AND APPLICATION OF THE SPECIFIC ANTIBODIES TO CYTOMEGALOVIRUS IN BONE MARROW TRANSPLANTATION[J].Academic Journal of Xi’an Jiaotong University,1998(1). |
| |
| Authors: | Zhang Met Liu Shaanxi Wang Baoyan Cat Ruibo Liu Xin Guo Guilt Dong Qing Skao Wenbln HanYunfeng |
| |
| Abstract: | using enzymellnked lmmunosorheut assay (ELlsA), we had determined the speclrlc antibodies of IgM and lgA to CMV In 14 patients with BAT, 36 marrow donors and 682 blood donorsfrom 1991 to 1996. The antibodies detected were negative in 14 patients, 16. 16% POsitive in marrowdonors and 34. 31 % in blood donors respectively. These resultS suggested that there was a higher active or recent CMV Inrectlou in blood donors in XI'an area. In order to prevent transfusion-acquiredCMV infectlony it is nessessary ror us to screen out negative CMV antibodies donors in BAT, whichhas great value for clinical application. |
| |
| Keywords: | bone marrow transplanation(BMT) cytmegalovirus(CMT) interstitial pneumonitis (IP) specific antibodies |
| 本文献已被 CNKI 等数据库收录！ |
