| EFFECTS OF OUABAIN AND DIGOXIN ON THE GENE EXPRESSION OFSODIUM PUMP α-SUBUNIT ISOFORM IN AORTIC SMOOTH MUSCLE OF RATS |
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| 作者姓名： | 原卫清 王颢 吕卓人 |
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| 作者单位： | Yuan Weiqing,Wang Hao,L Zhuoren Department of Cardiology,First Hospital of Xi'an Jiaotong University,Xi'an 710061,China |
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| 基金项目： | This project supported by the National Natural Science Foundation of China(No. 39670325). |
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| 摘 要： | Accumulating evidence indicates that endoge-nous ligands of the digitalis receptor may exist inthe mammalian body, which has recently been de-scribed to be indistinguishable from ouabainL1'2j.Endogenous ouabain (EO) might induce many cy-tobiological changes and play an important role inregulating water and sodium metabolism and vas-cular tone in the body["'J. Many studies haveshowed that EO content in both hypertensive pa-tients and hypertensive animals is much more thanthose of normal subje…
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