| 44例白血病免疫学表型分析 |
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| 引用本文： | 陈丽梅,刘陕西,杨玉琮,程小丽.44例白血病免疫学表型分析[J].西安交通大学学报(医学版),1997(4). |
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| 作者姓名： | 陈丽梅 刘陕西 杨玉琮 程小丽 |
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| 作者单位： | 西安第一临床医学院血液内科!西安710061 |
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| 摘 要： | 采用单克隆抗体（McAb）及流式细胞仪（FCM）测定了44例白血病的免疫表型。结果：有3种表型：系列专一性，系列非专一性，裸型。对其中3例进行了动态观察，发现在病程中免疫表型可以发生改变，且与病情及预后有关。
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| 关 键 词： | 白血病 免疫表型 单克隆抗体 流式细胞仪 |
IMMUNOPHENOTYING ANALYSIS OF LEUKEMIA IN 44 CASES |
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| Chen Limei, Liu Shanxi,Liang Chang'an et al.IMMUNOPHENOTYING ANALYSIS OF LEUKEMIA IN 44 CASES[J].Journal of Xi‘an Jiaotong University:Medical Sciences,1997(4). |
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| Authors: | Chen Limei Liu Shanxi Liang Chang'an |
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| Abstract: | Bone marrows from 44 cases of leukemia were evaluated by FAB classification in combination with flow cytornetric immunophenotyping (FCM-IM ). The McAbs were routinely,used, i. e. CD2, CD7, CD19, CD20, CD13, CD14,CD11b, CD33, CD41, and HLA-DR. 3 rnain patterns of immunophenotypes displayed: ① lineage SDecificantigen expression, ②aberration antigen expression (Ly+AML or M +ALL), ③Null type. From dynamic observation of the immunophenotypes of 3cases, we find that there was certain relationship between immunophenotype and the prognosis ofleukemia. |
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| Keywords: | leukemia immunophenotype monoclonal antibodies flow cytometry |
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