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| Peroxiredoxin1基因沉默对肝癌细胞HepG2和SMMC-7721放射增敏的研究 | |
| 引用本文： | 高麦仓,张龙,张殿增,张军.Peroxiredoxin1基因沉默对肝癌细胞HepG2和SMMC-7721放射增敏的研究[J].西安交通大学学报(医学版),2011,32(5):569-575. |
| 作者姓名： | 高麦仓 张龙 张殿增 张军 |
| 作者单位： | 1. 西安交通大学医学院第二附属医院消化科,陕西西安,710004 2. 西安交通大学医学院第一附属医院肿瘤放疗科,陕西西安,710061 3. 西安交通大学医学院实验中心,陕西西安,710061 |
| 摘 要： | 目的 探讨Peroxiredoxin (Prx)1基因的小分子干扰RNA(siRNA)对人肝癌细胞系HepG2和SMMC-7721的放射增敏作用及机制.方法 通过逆转录PCR方法研究Prx家族(Prx1～6)在人肝癌细胞HepG2和SMMC-7721中的mRNA表达谱；使用siRNA敲低HepG2和SMMC-7721细... |
| 关 键 词： | 肝癌细胞 放射敏感性 Peroxiredoxin 1 RNA干扰 细胞内活性氧 细胞周期阻滞 放射增敏 |
Sensitizing hepatocellular carcinoma cells HepG2 and SMMC-7721 to ionizing radiation by peroxiredoxin 1 silencing |
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| GAO Mai-cang,ZHANG Long,ZHANG Dian-zeng,ZHANG Jun.Sensitizing hepatocellular carcinoma cells HepG2 and SMMC-7721 to ionizing radiation by peroxiredoxin 1 silencing[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2011,32(5):569-575. | |
| Authors: | GAO Mai-cang ZHANG Long ZHANG Dian-zeng ZHANG Jun |
| Institution: | GAO Mai-cang1,ZHANG Long2,ZHANG Dian-zeng3,ZHANG Jun1 (1.Department of Gastroenterology,the Second Affiliated Hospital,Medical School ofXi'an Jiaotong University,Xi'an 710004,2.Department of Radiation Oncology,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University,Xi'an 710061,3.Department of Molecules Experimental Center,China) |
| Abstract: | |
| Keywords: | hepatocellular carcinoma cell radiosensitivity peroxiredoxin 1 RNA interference intracellular reactive oxygen species cell cycle arrest radiosensitizing |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |