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| 茴香枳术汤对粘连性肠梗阻大鼠血浆D-乳酸的影响 | |
| 引用本文： | 柳渊洁,王东红,盛丽,李亮,王自立,唐晓勇.茴香枳术汤对粘连性肠梗阻大鼠血浆D-乳酸的影响[J].西安交通大学学报(医学版),2011,32(5):640-642. |
| 作者姓名： | 柳渊洁 王东红 盛丽 李亮 王自立 唐晓勇 |
| 作者单位： | 1. 甘肃省中医院,甘肃兰州,730050 2. 兰州军区兰州总医院医务部,甘肃兰州,730050 3. 甘肃省中医院,甘肃兰州,730050;甘肃中医学院,甘肃兰州,730000 |
| 基金项目： | 甘肃省自然科学研究基金计划项目 |
| 摘 要： | 目的观察茴香枳术汤对粘连性肠梗阻大鼠血浆D-乳酸的影响,了解其在粘连性肠梗阻的作用机制。方法制备大鼠粘连性肠梗阻模型,随机分为正常组、模型组、大承气汤组及茴香枳术汤低(1.13 g/mL)、中(2.25 g/mL)、高(3.38 g/mL)剂量组。给予药物治疗后第3、5、7天,共3个时间点,每时间点6只;股动脉取血,Brandt法测定血浆D-乳酸含量。结果与正常组比较,模型组血浆D-乳酸含量显著增加(P<0.05);与模型组比较,大承气汤组及茴香枳术汤低剂量组、中剂量组和高剂量组血浆D-乳酸含量显著下降(P<0.01)。结论茴香枳术汤有很好的治疗粘连性肠梗阻的作用。其主要作用与恢复肠屏障功能有关。 |
| 关 键 词： | 粘连性肠梗阻 茴香枳术汤 D-乳酸 |
Effects of Huixiangzhizhu Soup on D-lactic acid in rats with adhesive intestinal obstruction |
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| LIU Yuan-jie,WANG Dong-hong,SHENG Li,LI Liang,WANG Zi-li,TANG Xiao-yong.Effects of Huixiangzhizhu Soup on D-lactic acid in rats with adhesive intestinal obstruction[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2011,32(5):640-642. | |
| Authors: | LIU Yuan-jie WANG Dong-hong SHENG Li LI Liang WANG Zi-li TANG Xiao-yong |
| Institution: | LIU Yuan-jie1,WANG Dong-hong2,SHENG Li1,LI Liang1,3,WANG Zi-li1,TANG Xiao-yong1(1.Gansu Hospital of TCM,Lanzhou 730050,2.Department of Medical Affairs,Lanzhou General Hospital of Lanzhou Military Command,3.Gansu College of TCM,Lanzhou 730000,China) |
| Abstract: | Objective To observe the effects of Huixiangzhizhu Soup(HX-S) on D-lactic acid in rats with adhesive intestinal obstruction and provide experimental evidence for the relationship between D-lactic acid change and adhesive intestinal obstruction of HX-S.Methods The Wistar rat model of adhesive intestinal obstruction was constructed.Totally 180 rats were randomly divided into normal group,model group,Dachengqi Soup(DS) group,HX-S low dosage(HX-SL) group(1.13 g/mL),HX-S medium dosage(HX-SM) group(2.25 g/mL) and... |
| Keywords: | adhesive intestinal obstruction Huixiangzhizhu Soup(HX-S) D-lactic acid |
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