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| 血府逐瘀汤对肋骨骨折伴血胸患者凝血功能的影响及疗效观察 | |
| 引用本文： | 张广健,高蕊,邱根全,付军科,金鑫.血府逐瘀汤对肋骨骨折伴血胸患者凝血功能的影响及疗效观察[J].西安交通大学学报(医学版),2011,32(5):632-635. |
| 作者姓名： | 张广健 高蕊 邱根全 付军科 金鑫 |
| 作者单位： | 1. 西安交通大学医学院第一附属医院胸外科,陕西西安,710061 2. 西安交通大学医学院第一附属医院核医学科,陕西西安,710061 3. 西安交通大学医学院第一附属医院中医科,陕西西安,710061 |
| 摘 要： | 目的观察血府逐瘀汤对肋骨骨折伴血胸患者凝血功能的影响及对血胸的治疗效果。方法肋骨骨折伴血胸患者随机、对照分组后,分别治疗。常规治疗组30例给予西药常规疗法,血府逐瘀汤组31例在此基础上加用血府逐瘀汤内服。两组均于入院后1、7、14 d进行D-二聚体(D-Di)、凝血4项检查以观察患者凝血功能改变;同时行CT检查,评估其对血胸的疗效。结果骨折后两组患者血液第14天的D-Di水平与入院第1天比较,明显降低(P<0.05)。而且,血府逐瘀汤组显著低于常规治疗组(P<0.05)。入院14 d后,两组凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)较入院时均有所延长,纤维蛋白原(FIB)随之减低。胸部CT检查评估血胸疗效,两组总有效率无显著性差异(100%、96.67%,P>0.05)。但是血府逐瘀汤组患者的平均住院天数显著缩短(13.25±1.48)d、(18.79±1.69)d,P<0.05]。结论血府逐瘀汤可改善血胸患者出现的血液高凝状态;同时,常规疗法辅以血府逐瘀汤既确保临床疗效,又显著缩短血胸患者的住院时间,对临床工作有一定的指导意义。 |
| 关 键 词： | 肋骨骨折 血胸 血府逐瘀汤 D-二聚体 高凝状态 CT检查 |
Treatment of hemothorax supplemented by Xuefu Zhuyu Decoction: Its curative effect and influence on coagulation state |
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| ZHANG Guang-jian,GAO Rui,QIU Gen-quan,FU Jun-ke,JIN Xin.Treatment of hemothorax supplemented by Xuefu Zhuyu Decoction: Its curative effect and influence on coagulation state[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2011,32(5):632-635. | |
| Authors: | ZHANG Guang-jian GAO Rui QIU Gen-quan FU Jun-ke JIN Xin |
| Institution: | ZHANG Guang-jian1,GAO Rui2,QIU Gen-quan3,FU Jun-ke1,JIN Xin1(1.Department of Thoracic Surgery,2.Department of Nuclear Medicine,3.Department of Traditional Medicine,the First Affiliated Hospital,Medical School of Xi'an Jiaotong University,Xi'an 710061,China) |
| Abstract: | Objective To observe the curative effect of Xuefu Zhuyu Decoction(XZD) on rib fracture and concomitant hemothorax and explore its influence on coagulation status in these patients.Methods Totally 61 patients were enrolled in this study.In addition to routine treatment(RT group,30 cases),the other 31 cases(XZD group) were treated by complementary XZD.CT scans were taken to compare the curative effects in the two groups.Prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),fibrino... |
| Keywords: | rib fracture hemothorax Xuefu Zhuyu Decoction D-dimer blood hypercoagu1aba1e state CT scan |
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