| C57/BL6小鼠海马发育和老化过程中Bcl-2及Bax的表达 |
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| 引用本文： | 李潮,张敬坤,张莉.C57/BL6小鼠海马发育和老化过程中Bcl-2及Bax的表达[J].西安交通大学学报(医学版),2011,32(5):553-556. |
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| 作者姓名： | 李潮 张敬坤 张莉 |
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| 作者单位： | 1. 辽宁医学院附属第一医院,辽宁锦州,121001
2. 辽宁医学院组织胚胎学教研室,辽宁锦州,121001 |
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| 摘 要： | 目的 观察C57/BL6小鼠海马发育老化过程中Bcl-2、Bax蛋白的表达变化.方法 取不同胚龄(embryonic day,E)、生后(postnatal day,P)日龄或月龄的小鼠海马,应用免疫组化及图像分析技术检测Bcl 2和Bax蛋白的表达.结果 E16 d～P7 d,海马CA区锥体细胞层和齿状回颗粒细胞层B...
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| 关 键 词： | 小鼠 海马 发育 Bcl-2 Bax |
Expression of Bcl-2 and Bax protein in the development and aging of C57/BL6 mouse hippocampus |
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| LI Chao,ZHANG Jing-kun,ZHANG Li.Expression of Bcl-2 and Bax protein in the development and aging of C57/BL6 mouse hippocampus[J].Journal of Xi‘an Jiaotong University:Medical Sciences,2011,32(5):553-556. |
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| Authors: | LI Chao ZHANG Jing-kun ZHANG Li |
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| Institution: | LI Chao1,ZHANG Jing-kun2,ZHANG Li2(1.the First Affiliated Hospital,2.Department of Histology and Embryology,Liaoning Medical College,Jinzhou 121001,China) |
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| Abstract: | Objective To observe the changes of expression of Bcl-2 and Bax protein in the development and aging of C57/BL6 mouse hippocampus.Methods Immunohistochemical and image analysis methods were used to detect the expression of Bcl-2 and Bax protein in the mouse hippocampus of different age.Results From embyronic(E) 16 day(d) to postnatal day(P) 7 d,Bcl-2 and Bax immunoreactive cells increased in the pyramidal layer and granular layer,and the average optical(AO) increased too.From P14 d to P21 d,immunoreactive c... |
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| Keywords: | mouse hippocampus development Bcl-2 Bax |
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