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联合化疗加山莨菪碱治疗复治肺结核疗效观察
引用本文:仵春云,张成基. 联合化疗加山莨菪碱治疗复治肺结核疗效观察[J]. 西安交通大学学报(医学版), 1997, 0(1)
作者姓名:仵春云  张成基
作者单位:西安第一附属医院卫防科 西安710061(仵春云),陕西省结核病防治院内一科 西安710100(张成基)
摘    要:
对33例复治肺结核患者以HRZS/HRE或HRZE方案加山莨菪碱进行治疗,观察其疗效。结果表明疗程结束时山莨菪碱治疗组痰菌阴转率、病灶吸收率、空洞闭合率分别达到92.6%、81.8%和81.6%,均明显高于对照组(P<0.05)。认为此方法对经不规则化疗的复治肺结核疗效满意,尤其对慢性纤维空洞患者空洞闭合率高。并就山莨菪碱治疗肺结核增强疗效的可能机制进行了探讨。

关 键 词:复治肺结核  山莨菪碱  化疗

OBSERVATIONS ON THE TREATMENT OF RETHERAPEUTIC PULMONARY TUBERCULOSIS WITH COMBINATION CHEMOTHERAPY PLUS ANISODAMINE
Wu Chunyun, Zhang Chengji. OBSERVATIONS ON THE TREATMENT OF RETHERAPEUTIC PULMONARY TUBERCULOSIS WITH COMBINATION CHEMOTHERAPY PLUS ANISODAMINE[J]. Journal of Xi‘an Jiaotong University:Medical Sciences, 1997, 0(1)
Authors:Wu Chunyun   Zhang Chengji
Abstract:
23 cases of retherapeutic pulmonarytuberculosis treated with combination chemotherapyPlus anisodamine (654-2) were observed. The results showed that the sterilization rate of the sputum, focal absorbance and cavity occlusion in chest roentgenograms were 92. 6%, 81. 8% and 87. 2%respectively. Compared with the controls they werehigher(P<0.05). These data suggest that combination chernotherapy plus anisodamine is an effective method in the treatment of retherapeutic pulmonary tubtrculosis,especially chronic fibro-cavitative pulmonary tuberculosis.In addition,we approached the anisodamine's mechanism that can enhance thetherapeutic effect on treating pulmonary tuberculosis.
Keywords:retherapeutic pulmonary tuberculosis   anisodamine(654-2)   chemotherapy
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