| 基于近似约简的基因选择方法 |
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| 引用本文： | 祁云嵩,孙怀江,宋余庆,谢军. 基于近似约简的基因选择方法[J]. 江苏科技大学学报(社会科学版), 2009, 23(1) |
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| 作者姓名： | 祁云嵩 孙怀江 宋余庆 谢军 |
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| 作者单位： | 南京理工大学,计算机科学与技术学院,江苏,南京,210094;江苏科技大学,计算机科学与工程学院,江苏,镇江,212003;南京理工大学,计算机科学与技术学院,江苏,南京,210094 |
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| 摘 要： | 为了对癌症等疾病分型、诊断及进行病理学研究,利用基因微阵列数据识别疾病相关基因.考虑到了基因微阵列数据是典型的矛盾决策系统,在证明矛盾系统在近似分布集上是协调的这一事实的基础上提出了一套近似分布约简理论,讨论了不同近似分布集上约简之间的关系,提出了基于近似约简的基因选择方法.使用两组真实的基因表达数据对所提出的方法进行了验证.实验结果表明,该方法能在保持分类能力的情况下降低特征基因集的相关性,从而显著地减少特征基因的数量.
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| 关 键 词： | 基因微阵列 基因选择 序值决策系统 |
A gene selection method based on approximate reduction |
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| Qi Yunsong,,Sun Huaijiang,Song Yuqing,Xie Jun. A gene selection method based on approximate reduction[J]. Journal of Jiangsu University of Science and Technology(Natural Science Edition), 2009, 23(1) |
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| Authors: | Qi Yunsong Sun Huaijiang Song Yuqing Xie Jun |
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| Affiliation: | 1.School of Computer Science and Technology;Nanjing University of Science and Technology;Nanjing Jiangsu 210094;China;2.School of Computer Science and Engineering;Jiangsu University of Science and Technology;Zhenjiang Jiangsu 212003;China |
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| Abstract: | To identify disease related genes from gene expression profiles(DNA microarray) has a very important practical significance for disease,such as cancer,subtype discovery,diagnosis and pathology study.Gene selection is a critical preprocessing technique for the DNA microarray data analysis.Gene sets of interest typically selected by usual ranking methods from DNA microarray data will contain many highly correlated genes and remain high dimension.Thinking of that DNA microarray data sets are typical inconsiste... |
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| Keywords: | DNA microarray gene selection ordered decision system |
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